Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
461-05-014 ISMRM Abstract

Physics-informed synthesis of contrast agent-free DSC parameters and novel MR biomarkers

Primary: Acquisition & Reconstruction
Secondary: Physics & Engineering
461-05-014 · Advances in Neuroimaging and Biomarkers for Brain Health and Disease · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row B
Keywords: Physics-informed neural network Contrast-agent free DSC parameter synthesis Novel MR biomarkers
Accepted
Lu Wang1, Zhen Xing2, Congbo Cai1, Dairong Cao2, QING LI3, Shuhui Cai 1
1Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen, China
2Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China
3MR Research Collaboration Team, Siemens Healthineers Ltd, Shanghai, China
Presenting Author: Shuhui Cai

Synopsis

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References

1. Anzalone N, Castellano A, Cadioli M, et al. Brain gliomas: Multicenter standardized assessment of dynamic contrast-enhanced and dynamic susceptibility contrast MR images. Radiology 2018;287(3):933-943.
2. Ramalho J, Semelka RC, Ramalho M, Nunes RH, AlObaidy M, Castillo M. Gadolinium-based contrast agent accumulation and toxicity: An update. American Journal of Neuroradiology 2016;37(7):1192-1198.
3. Rogosnitzky M, Branch S. Gadolinium-based contrast agent toxicity: A review of known and proposed mechanisms. Biometals 2016;29(3):365-376.
4. Sainz-DeMena D, Pérez MA, García-Aznar JM. Exploring the potential of physics-informed neural networks to extract vascularization data from DCE-MRI in the presence of diffusion. Medical Engineering & Physics 2024;123:104092.
5. Lebihan D, Turner R. The capillary network: A link between IVIM and classical perfusion. Magnetic Resonance in Medicine 1992;27(1):171-178.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/461-05-014