Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
570-05-200 ISMRM Abstract

Motion-robust Z-spectral MRI with keyhole acquisition detects β₃-adrenergic–induced browning in visceral fat depots.

Primary: Preclinical Animal & in vitro MR - Biomarkers
Secondary: Contrast Mechanisms - CEST / APT / NOE
570-05-200 · MRI of Brown Adipose Tissue: Feel the Heat · Wednesday, 13 May, 1:40 PM–2:35 PM · Traditional Posters | Exhibition Hall
Keywords: Molecular Imaging Motion robust Accelerated CEST MRI Browning Visceral Adipose Tissue
Accepted
Zoheb Ahasan 1,2, Zimeng Cai3, Amar Kumar4, Qiaoling Zhong5, Weiguo Li1,6, Chongwee Liew4, Kejia Cai6,7,8
1Department of Biomedical Engineering, University of Illinois Chicago, Chicago, United States of America
2Department of Radiology, University of Illinois Chicago, Chicago, United States of America
3Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, GuangDong, Guangzhou, China
4Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, United States of America
5Department of Radiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, China
6University of Illinois Chicago, Chicago, United States of America
7University of Illinois at Chicago, Chicago, United States of America
8Department of Radiology and Biomedical Engineering, University of Illinois at Chicago, Chicago, United States of America
Presenting Author: Zoheb Ahasan

Synopsis

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References

1. van Zijl PC, Yadav NN. Chemical exchange saturation transfer (CEST): what is in a name and what isn't? Magn Reson Med. 2011 Apr;65(4):927-48. doi: 10.1002/mrm.22761. Epub 2011 Feb 17. PMID: 21337419; PMCID: PMC3148076. [doi] [pmid]
2. Cai Z, Zhong Q, Feng Y, Wang Q, Zhang Z, Wei C, Yin Z, Liang C, Liew CW, Kazak L, Cypess AM, Liu Z, Cai K. Non-invasive mapping of brown adipose tissue activity with magnetic resonance imaging. Nat Metab. 2024 Jul;6(7):1367-1379. doi: 10.1038/s42255-024-01082-z. Epub 2024 Jul 25. PMID: 39054361; PMCID: PMC11272596. [doi] [pmid]
3. Scotti A, Tain RW, Li W, Gil V, Liew CW, Cai K. Mapping brown adipose tissue based on fat water fraction provided by Z-spectral imaging. J Magn Reson Imaging. 2018 Jun;47(6):1527-1533. doi: 10.1002/jmri.25890. Epub 2017 Nov 17. PMID: 29148120; PMCID: PMC5957768. [doi] [pmid]
4. Li J, Wang L, Wu S, Yang G, Zhang LJ. Imaging Brown Adipose Tissue: Current State and Future Perspective. Theranostics. 2025 Aug 16;15(17):9001-9018. doi: 10.7150/thno.111643. PMID: 40963911; PMCID: PMC12439256. [doi] [pmid]
5. Finlin BS, Memetimin H, Confides AL, Kasza I, Zhu B, Vekaria HJ, Harfmann B, Jones KA, Johnson ZR, Westgate PM, Alexander CM, Sullivan PG, Dupont-Versteegden EE, Kern PA. Human adipose beiging in response to cold and mirabegron. JCI Insight. 2018 Aug 9;3(15):e121510. doi: 10.1172/jci.insight.121510. PMID: 30089732; PMCID: PMC6129119. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/570-05-200