Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
468-02-002 ISMRM Abstract

Assessing the Oxygen Extraction Fraction in Type Ⅱ Diabetes Mellitus and the relationship with cognitive impairment.

Primary: Brain Function and fMRI - fMRI & Neuromodulation
Secondary: Neuro - Peripheral Nerves
468-02-002 · Type 2 Diabetes · Tuesday, 12 May, 9:15 AM–10:10 AM · Digital Posters Row I
Accepted
Shurong Wu 1, Fushuai Zhang1, Zhenyu Cheng1, Yiwen Chen2, Pengcheng Liang2, Xinxin Huo2, Boyao Chen2, Jiaxiang xin3, Qihao Zhang4, Meng Li5, Changhu Liang2, Lingfei Guo2
1Binzhou Medical University, Yantai City, Shandong Province, China
2Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
3MR Collaborations, Siemens Healthineers Ltd., Shanghai, China
4Weill Cornell Medical College, New York, United States of America
5Jena University Hospital, Jena, Germany
Presenting Author: Shurong Wu

Synopsis

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References

1. Cullinane, P. W. et al. Type 2 Diabetes and Parkinson’s Disease: A Focused Review of Current Concepts. Mov. Disord. 38, 162–177 (2023).
2. Ding, X. et al. Diabetes accelerates Alzheimer’s disease progression in the first year post mild cognitive impairment diagnosis. Alzheimers Dement. 20, 4583–4593 (2024).
3. Liu, D. et al. Multi-Parametric Evaluation of Cerebral Hemodynamics in Neonatal Piglets Using Non-Contrast-Enhanced Magnetic Resonance Imaging Methods. J. Magn. Reson. Imaging 54, 1053–1065 (2021).
4. Cho, J. et al. Cerebral metabolic rate of oxygen (CMRO2 ) mapping by combining quantitative susceptibility mapping (QSM) and quantitative blood oxygenation level‐dependent imaging (qBOLD). Magn. Reson. Med. 80, 1595–1604 (2018).
5. Yang, L. et al. Oxygen extraction fraction (OEF) assesses cerebral oxygen metabolism of deep gray matter in patients with pre-eclampsia. Eur. Radiol. 32, 6058–6069 (2022).
6. Liu, Z., Spincemaille, P., Yao, Y., Zhang, Y. & Wang, Y. MEDI+0: Morphology enabled dipole inversion with automatic uniform cerebrospinal fluid zero reference for quantitative susceptibility mapping. Magn. Reson. Med. 79, 2795–2803 (2018).
7. Bangen, K. J. et al. Reduced Regional Cerebral Blood Flow Relates to Poorer Cognition in Older Adults With Type 2 Diabetes. Front. Aging Neurosci. 10, 270 (2018).
8. Barloese, M. C. J. et al. Neurovascular Coupling in Type 2 Diabetes With Cognitive Decline. A Narrative Review of Neuroimaging Findings and Their Pathophysiological Implications. Front. Endocrinol. 13, 874007 (2022).
9. Park, J., Chun, J., Park, H., Kim, E. & Kim, J. Involvement of amygdala–prefrontal dysfunction in the influence of negative emotion on the resolution of cognitive conflict in patients with schizophrenia. Brain Behav. 8, e01064 (2018).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/468-02-002