Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
460-03-011 ISMRM Abstract

Early prediction of pathologic complete response to neoadjuvant chemotherapy based on longitudinal total choline of MR spectr

Primary: Body - Breast
Secondary: Brain Function and fMRI
460-03-011 · Image Classification for Breast Cancer · Tuesday, 12 May, 1:40 PM–2:35 PM · Digital Posters Row A
Keywords: 1H MRS Breast Tumor
Accepted
XUEQIN GONG 1, SHULING LIU1, Ting Yin2
1Department of Radiology Chongqing University Cancer Hospital, Chongqing, chongqing, China
2MR Collaborations, Siemens Healthineers Ltd., Shanghai, China
Presenting Author: XUEQIN GONG

Synopsis

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References

1. 1. Kumar, M., et al., Monitoring the therapeutic response of locally advanced breast cancer patients: sequential in vivo proton MR spectroscopy study. Journal of magnetic resonance imaging: JMRI, 2006. 24(2): p. 325-32.
2. 2. Jagannathan, N., et al., Evaluation of total choline from in-vivo volume localized proton MR spectroscopy and its response to neoadjuvant chemotherapy in locally advanced breast cancer. British journal of cancer, 2001. 84(8): p. 1016-22.
3. 3. Choi, J., et al., Magnetic resonance metabolic profiling of estrogen receptor-positive breast cancer: correlation with currently used molecular markers. Oncotarget, 2017. 8(38): p. 63405-63416.
4. 4. Haddadin, I., et al., Metabolite quantification and high-field MRS in breast cancer. NMR in biomedicine, 2009. 22(1): p. 65-76.
5. 5. DANISHAD K, SHARMA U, SAH R, et al. Assessment of therapeutic response of locally advanced breast cancer (LABC) patients undergoing neoadjuvant chemotherapy (NACT) monitored using sequential magnetic resonance spectroscopic imaging (MRSI) [J]. NMR in biomedicine, 2010, 23(3): 233-41.
6. 6. GALATI F, LUCIANI M, CARAMANICO C, et al. Breast Magnetic Resonance Spectroscopy at 3 T in Biopsy-Proven Breast Cancers: Does Choline Peak Correlate With Prognostic Factors? [J]. Investigative radiology, 2019, 54(12): 767-73.
7. 7. WANG X, WANG X, SONG H, et al. 1H-MRS evaluation of breast lesions by using total choline signal-to-noise ratio as an indicator of malignancy: a meta-analysis [J]. Medical oncology (Northwood, London, England), 2015, 32(5): 160.
8. 8. JAGANNATHAN N. Application of in vivo MR methods in the study of breast cancer metabolism [J]. NMR in biomedicine, 2019, 32(10): e4032.
9. 9. DRISIS S, FLAMEN P, IGNATIADIS M, et al. Total choline quantification measured by 1H MR spectroscopy as early predictor of response after neoadjuvant treatment for locally advanced breast cancer: The impact of immunohistochemical status [J]. Journal of magnetic resonance imaging : JMRI, 2018, 48(4): 982-93.

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http://echo.ismrm.org/p/ISMRM2026/460-03-011