Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
307-04-002 / 271-01-058 ISMRM Abstract

Efficient High-Resolution Fat-Fraction Mapping for Myocardial Fat and Semaglutide Response in a Porcine HFpEF Model

Primary: Cardiovascular - Heart Failure
Secondary: Acquisition & Reconstruction - Quantitative Imaging: chest, abdomen, and pelvis
307-04-002 · Heart Failure · Monday, 11 May, 4:10 PM–6:00 PM · Meeting Room 1.40
271-01-058 · ISMRM AMPC Selected Posters · Sunday, 10 May, 7:00 AM–2:00 PM · Traditional Posters
Keywords: Fat and Fat/Water Separation Free-running MRI Therapeutic response Heart failure with preserved ejection fraction 3D multi-echo GRE
Accepted
Xinheng Zhang1, Mahmoud Elbatrik2, Yuheng Huang1, Archana Malagi1, Chia Chi Yang1,2, Li-Ting Huang3,4, Miguel Huerta2, David Lefer2, Traci Goodchild2, Hsin-Jung Yang 1
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, United States of America
2Cedars-Sinai Medical Center, Los Angeles, United States of America
3National Cheng Kung University, Tainan, Taiwan
4National Cheng Kung University Hospital, Tainan, Taiwan
Presenting Author: Hsin-Jung Yang

Synopsis

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References

1. 1. Felker GM. Toward a New SUMMIT in Heart Failure with Preserved Ejection Fraction. New England Journal of Medicine. 2025;392(5):505-506. doi:10.1056/NEJMe2415551 [doi]
2. 2. Sharp TE, Scarborough AL, Li Z, et al. Novel Göttingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities. JACC: Basic to Translational Science. 2021;6(2):154-170. doi:10.1016/j.jacbts.2020.11.012 [doi]
3. 3. Guan X, Yang HJ, Zhang X, et al. Non-electrocardiogram-gated, free-breathing, off-resonance reduced, high-resolution, whole-heart myocardial T(2) * mapping at 3 T within 5 min. Magn Reson Med 2024;91(5):1936-1950.
4. 4. Huang Y, Guan X, Zhang X, et al. Accurate Intramyocardial Hemorrhage Assessment with Fast, Free-running, Cardiac Quantitative Susceptibility Mapping. Radiol Cardiothorac Imaging. 2024;6(6):e230376. doi:10.1148/ryct.230376 [doi]
5. 5. Bydder M, Ghodrati V, Gao Y, et al. Constraints in estimating the proton density fat fraction. Magn Reson Imaging 2020;66:1-8.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/307-04-002