Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
361-05-011 ISMRM Abstract

Optimizing relaxation-exchange magnetic resonance imaging for parameter mapping in white matter

Primary: Acquisition & Reconstruction - Quantitative Imaging: head and neck
Secondary: Neuro - White Matter
361-05-011 · Quantitative Imaging: Head and Neck I · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row B
Keywords: Pulse Sequence Design White Matter Magnetic Resoance Fingerprinting Quantitative Magnetic Resonance Imaging
Accepted
Cyrus Najarian 1, Navid Seraji-Bozorgzad2,3, Scott D Swanson4,5, Nicole Seiberlich1,2,4, Jon-Fredrik Nielsen1,2,4,6,7, Jeffrey A Fessler1,4,8
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, United States of America
2University of Michigan, Ann Arbor, United States of America
3Department of Neurology, University of Michigan, Ann Arbor, United States of America
4Department of Radiology, University of Michigan, Ann Arbor, United States of America
5Department of Biophysics, University of Michigan, Ann Arbor, United States of America
6Functional MRI Laboratory, Department of Radiology, University of Michigan, Ann Arbor, United States of America
7Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, United States of America
8Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, United States of America
Presenting Author: Cyrus Najarian

Synopsis

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References

1. Van Der Weijden, C. W. J., Biondetti, E., Gutmann, I. W., Dijkstra, H., Mckerchar, R., De Paula Faria, D., De Vries, E. F. J., Meilof, J. F., Dierckx, R. A. J. O., Prevost, V. H., & Rauscher, A. (2023). Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status. Brain, 146(4), 1243-1266. https://doi.org/10.1093/brain/awac436 [doi]
2. Wu, X., He, Q., Yin, Y., Tan, S., Zhang, B., Li, W., Hsu, Y.-C., Xue, R., & Bai, R. (2024 Nov 26). Relaxation-exchange magnetic resonance imaging (REXI): a non-invasive imaging method for evaluating trans-barrier water exchange in the choroid plexus. Fluids and Barriers of the CNS, 21(1). https://doi.org/10.1186/s12987-024-00589-7 [doi]
3. Wu X, Tan S, Zhang Y, et al. Feasibility of relaxation-exchange magnetic resonance imaging (REXI) for measuring water exchange across the blood–CSF barrier in the human choroid plexus. Journal of Cerebral Blood Flow & Metabolism. 2025;0(0). https://doi.org/10.1177/0271678x251369218 [doi]
4. Ma, D., Gulani, V., Seiberlich, N., Liu, K., Sunshine, J. L., Duerk, J. L., & Griswold, M. A. (2013-03-13). Magnetic resonance fingerprinting. Nature 2013 495:7440, 495(7440). https://doi.org/10.1038/nature11971 [doi]
5. Nataraj, G., Nielsen, J.F., Scott, C. and Fessler, J.A., 2018. Dictionary-free MRI PERK: Parameter estimation via regression with kernels. IEEE transactions on medical imaging, 37(9), pp.2103-2114. https://doi.org/10.1109/TMI.2018.2817547 [doi]
6. Collins, D.L., Zijdenbos, A.P., Kollokian, V., Sled, J.G., Kabani, N.J., Holmes, C.J. and Evans, A.C., 1998. Design and construction of a realistic digital brain phantom. IEEE transactions on medical imaging, 17(3), pp.463-468. https://doi.org/10.1109/42.712135 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/361-05-011