667-04-012 · Novel Visualization and Assessment of Osseous Tissues
· Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row H
Keywords:Tendon/LigamentT2 star mappingKnee cartilageBiomechanicsDiffusion-weighted imaging (DWI)
Accepted
Carly A Lockard1,2, Roberto A Pineda Guzman1,2, Carson Osmond3, Evelyn Bombard1, Ruei-yuan Tu1, Kaviamuthan Kanakaraju1,4, Mariana E Kersh3,4,5, Christina M Laukaitis1,4,6, Bruce M Damon 1,2,3,5,7,8
1Stephens Family Clinical Research Institute, Carle Health, Urbana, United States of America
2Carle Illinois Advanced Imaging Center, Urbana, United States of America
3University of Illinois at Urbana-Champaign, Champaign, United States of America
4Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Champaign, United States of America
5Beckman Institute, University of Illinois at Urbana-Champaign, Champaign, United States of America
6Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Champaign, United States of America
7Vanderbilt University, Nashville, United States of America
8Vanderbilt University Institute of Imaging Science, Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, United States of America
Presenting Author: Bruce M Damon
Synopsis
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1. Castori M. Ehlers-Danlos Syndrome, Hypermobility Type: An Underdiagnosed Hereditary Connective Tissue Disorder with Mucocutaneous, Articular, and Systemic Manifestations. ISRN Dermatol. 2012 Nov 22;2012:1–22. doi: 10.5402/2012/751768 [doi]
2. Heighes LA, Abelleyra Lastoria DA, Beni R, Iftikhar A, Hing CB. The relationship between joint hypermobility and patellar instability: A systematic review. J Orthop. 2024 Oct;56:40–9. doi: 10.1016/j.jor.2024.05.009 [doi]
3. Rombaut L, De Paepe A, Malfait F, Cools A, Calders P. Joint position sense and vibratory perception sense in patients with Ehlers–Danlos syndrome type III (hypermobility type). Clin Rheumatol. 2010 Mar;29(3):289–95. doi: 10.1007/s10067-009-1320-y [doi]
4. Stern CM, Pepin MJ, Stoler JM, Kramer DE, Spencer SA, Stein CJ. Musculoskeletal Conditions in a Pediatric Population with Ehlers-Danlos Syndrome. J Pediatr. 2017 Feb;181:261–6. doi: 10.1016/j.jpeds.2016.10.078 [doi]
5. Brisson NM, Krämer M, Krahl LAN, Schill A, Duda GN, Reichenbach JR. A novel multipurpose device for guided knee motion and loading during dynamic magnetic resonance imaging. Z Für Med Phys. 2022 Nov;32(4):500–13. doi: 10.1016/j.zemedi.2021.12.002 [doi]
6. Williams A, Qian Y, Chu CR. UTE-T2∗ mapping of human articular cartilage in vivo: a repeatability assessment. Osteoarthritis Cartilage. 2011 Jan;19(1):84–8. doi: 10.1016/j.joca.2010.10.018 [doi]
7. Williams A, Qian Y, Golla S, Chu CR. UTE-T2∗ mapping detects sub-clinical meniscus injury after anterior cruciate ligament tear. Osteoarthritis Cartilage. 2012 Jun;20(6):486–94. doi: 10.1016/j.joca.2012.01.009 [doi]
8. Chu CR, Williams AA. Quantitative MRI UTE-T2* and T2* Show Progressive and Continued Graft Maturation Over 2 Years in Human Patients After Anterior Cruciate Ligament Reconstruction. Orthop J Sports Med. 2019 Aug;7(8):232596711986305. doi: 10.1177/2325967119863056 [doi]
9. Schmitz RJ, Wang HM, Kraft RA, Shultz SJ, Ross SE, Henson RA, et al. Regional differences in anterior cruciate ligament imaging biomarkers: T2 and T2* values. Muscle Ligaments Tendons J. 2019 Jan;08(02):238. doi:10.32098/mltj.02.2018.13 [doi]
10. Wilms LM, Radke KL, Latz D, Thiel TA, Frenken M, Kamp B, et al. UTE-T2* versus conventional T2* mapping to assess posterior cruciate ligament ultrastructure and integrity—an in-situ study. Quant Imaging Med Surg. 2022 Aug;12(8):4190–201. doi: 10.21037/qims-22-251 [doi]
11. Raya JG, Horng A, Dietrich O, Krasnokutsky S, Beltran LS, Storey P, et al. Articular Cartilage: In Vivo Diffusion-Tensor Imaging. Radiology. 2012 Feb;262(2):550–9. doi: 10.1148/radiol.11110821 [doi]
12. Duarte A, Ruiz A, Ferizi U, Bencardino J, Abramson SB, Samuels J, et al. Diffusion tensor imaging of articular cartilage using a navigated radial imaging spin-echo diffusion (RAISED) sequence. Eur Radiol. 2019 May;29(5):2598–607. doi: 10.1007/s00330-018-5780-9 [doi]
13. Liu S, Liu J, Chen W, Zhang L, Wu S, Wang F, et al. Diffusion Tensor Imaging for Quantitative Assessment of Anterior Cruciate Ligament Injury Grades and Graft. J Magn Reson Imaging. 2020 Nov;52(5):1475–84. doi: 10.1002/jmri.27322 [doi]
14. Van Dyck P, Billiet T, Desbuquoit D, Verdonk P, Heusdens CH, Roelant E, et al. Diffusion tensor imaging of the anterior cruciate ligament graft following reconstruction: a longitudinal study. Eur Radiol. 2020 Dec;30(12):6673–84. doi: 10.1007/s00330-020-07051-w [doi]
15. Rombaut L, Malfait F, De Wandele I, Mahieu N, Thijs Y, Segers P, et al. Muscle–tendon tissue properties in the hypermobility type of Ehlers‐Danlos syndrome. Arthritis Care Res. 2012 May;64(5):766–72. doi: 10.1002/acr.21592 [doi]
16. Wang TJ, Stecco A, Hakim AJ, Schleip R. Fascial Pathophysiology in Hypermobility Spectrum Disorders and Hypermobile Ehlers–Danlos Syndrome: A Review of Emerging Evidence. Int J Mol Sci. 2025 Jun 11;26(12):5587. doi: 10.3390/ijms26125587 [doi]
17. Meira EP, Brumitt J. Influence of the hip on patients with patellofemoral pain syndrome: a systematic review. Sports Health. 2011 Sep;3(5):455–65. doi: 10.1177/1941738111415006 [doi]
18. Beveridge JE, Machan JT, Walsh EG, Kiapour AM, Karamchedu NP, Chin KE, et al. Magnetic resonance measurements of tissue quantity and quality using T 2 * relaxometry predict temporal changes in the biomechanical properties of the healing ACL. J Orthop Res. 2018 Jun;36(6):1701–9. doi: 10.1002/jor.23830 [doi]
19. Biercevicz AM, Proffen BL, Murray MM, Walsh EG, Fleming BC. T 2 * relaxometry and volume predict semi-quantitative histological scoring of an ACL bridge-enhanced primary repair in a porcine model. J Orthop Res. 2015 Aug;33(8):1180–7. doi: 10.1002/jor.22874 [doi]
20. Figueroa A, Bugajski T, Humpal D, Kumaravel M, Lowe W, Zandiyeh P. Relationship Between Quantitative MRI UTE T2* of ACL Autografts and BMI-Normalized Knee Laxity Within the First Year After ACL Reconstruction. Am J Sports Med. 2025 Oct;53(12):2841-2850. doi: 10.1177/03635465251368393. [doi]
21. Emanuel KS, Kellner LJ, Peters MJM, Haartmans MJJ, Hooijmans MT, Emans PJ. The relation between the biochemical composition of knee articular cartilage and quantitative MRI: a systematic review and meta-analysis. Osteoarthritis Cartilage. 2021 Nov;S1063458421009766. doi: 10.1016/j.joca.2021.10.016 [doi]
22. Pownder SL, Hayashi K, Lin BQ, Meyers KN, Caserto BG, Breighner RE, et al. Differences in the magnetic resonance imaging parameter T2* may be identified during the course of canine patellar tendon healing: a pilot study. Quant Imaging Med Surg. 2021 Apr;11(4):1234–46. doi: 10.21037/qims-20-684 [doi]