Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
302-04-008 ISMRM Abstract

Early Therapy Response Assessment in Pancreatic Ductal Adenocarcinoma Using Quantitative DCE-MRI

Primary: Contrast Mechanisms - Perfusion
Secondary: Acquisition & Reconstruction - Quantitative Imaging: chest, abdomen, and pelvis
302-04-008 · Mapping Liver and Pancreas Health · Monday, 11 May, 4:10 PM–6:00 PM · Hall 1B
Keywords: DCE-MRI Pancreatic ductal adenocarcinoma Therapy monitoring Perfusion phantom Multi-site validation
Accepted
Ezinwanne E Onuoha1, Martin D Holland2, Darryl A Outlaw2, Midhun Malla2, Mehmet Akce2, Salila Hashmi3, Sushanth Reddy3, Bart Rose3, Desiree Morgan4, Grant R Williams5, Moh'd Khushman6, Dana B Cardin7, Kate C Frederick-Dyer8, Xiaoyu Jiang8, Bassel El-Rayes2, Junzhong Xu8, Harrison Kim9
1Department of Biomedical Engineering, The Ohio State University, Columbus, United States of America
2Department of Medicine, University of Alabama at Birmingham, Birmingham, United States of America
3Department of Surgery, University of Alabama at Birmingham, Birmingham, United States of America
4Department of Radiology, University of Alabama at Birmingham, Birmingham, United States of America
5DCH Regional Medical Center, Tuscaloosa, United States of America
6Department of Medicine, Washington University in St. Louis, St. Louis, United States of America
7Department of Medicine, Vanderbilt University Medical Center, Nashville, United States of America
8Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, United States of America
9Department of Radiology, The Ohio State University, Columbus, United States of America
Presenting Author: Juliet Varghese

Synopsis

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References

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2. Walter FM, Mills K, Mendonça SC, Abel GA, Basu B, Carroll N, Ballad S, Lancaster J, Hamilton W, Rubin GP, Emery JD. Symptoms and patient factors associated with diagnostic intervals for pancreatic cancer (SYMPTOM pancreatic study): a prospective cohort study. Lancet Gastroenterol Hepatol. (2016) 1:298–306. PMID: 28404200 PMCID: PMC6358142 DOI: 10.1016/S2468-1253(16)30079-6. [doi] [pmid]
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5. Kim H. Variability in Quantitative DCE-MRI: Sources and Solutions. J Nat Sci. 2018;4(1). Epub 2018/03/13. PubMed PMID: 29527572; PMCID: PMC5841165. [pmid]
6. Kim H, Mousa M, Schexnailder P, Hergenrother R, Bolding M, Ntsikoussalabongui B, Thomas V, Morgan DE. Portable perfusion phantom for quantitative DCE-MRI of the abdomen. Med Phys. 2017;44(10):5198-209. Epub 2017/07/12. doi: 10.1002/mp.12466. PubMed PMID: 28692137; PMCID: PMC5646228. [doi] [pmid]
7. Holland MD, Morales A, Simmons S, Smith B, Misko SR, Jiang X, Hormuth DA, Christenson C, Koomullil RP, Morgan DE, Li Y, Xu J, Yankeelov TE, Kim H. Disposable point-of-care portable perfusion phantom for quantitative DCE-MRI. Med Phys. 2022;49(1):271-81. Epub 20211210. doi: 10.1002/mp.15372. PubMed PMID: 34802148. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/302-04-008