David G.J. Heesterbeek 1, Max H.C. van Riel1, Ray Sheombarsing1, Tristan van Leeuwen2,3, Martijn Froeling4, Cornelis A van den Berg1, Alessandro A Sbrizzi1
1Computational Imaging Group for MRI Therapy & Diagnostics, Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
2Mathematical Institute, Utrecht University, Utrecht, Netherlands
3Computational Imaging Group, Centrum Wiskunde & Informatica, Amsterdam, Netherlands
4Precision Imaging Group, Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands
Presenting Author: David G.J. Heesterbeek
Synopsis
Motivation:
Goals:
Approach:
Results:
Full abstract & presentation
The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.
Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.
To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.
1. V. Mazzoli et al., “Accelerated 4D phase contrast MRI in skeletal muscle contraction,” Magn. Reson. Med., vol. 80, no. 5, pp. 1799–1811, Nov. 2018, doi: 10.1002/mrm.27158. [doi]
2. J. A. Kent-Braun and R. G. Miller, “Central fatigue during isometric exercise in amyotrophic lateral sclerosis,” Muscle Nerve, vol. 23, no. 6, pp. 909–914, 2000, doi: 10.1002/(SICI)1097-4598(200006)23:6<909::AID-MUS10>3.0.CO;2-V. [doi]
3. J. A. Kent-Braun et al., “Strength, skeletal muscle composition, and enzyme activity in multiple sclerosis,” J. Appl. Physiol., vol. 83, no. 6, pp. 1998–2004, Dec. 1997, doi: 10.1152/jappl.1997.83.6.1998. [doi]
4. J. C. Villalobos Lizardi et al., “A guide for assessment of myocardial stiffness in health and disease,” Nat. Cardiovasc. Res., vol. 1, no. 1, pp. 8–22, Jan. 2022, doi: 10.1038/s44161-021-00007-3. [doi]
5. R. Muthupillai, D. J. Lomas, P. J. Rossman, J. F. Greenleaf, A. Manduca, and R. L. Ehman, “Magnetic Resonance Elastography by Direct Visualization of Propagating Acoustic Strain Waves,” Science, vol. 269, no. 5232, pp. 1854–1857, Sep. 1995, doi: 10.1126/science.7569924. [doi]
6. L. E. Bilston, “Soft tissue rheology and its implications for elastography: Challenges and opportunities,” NMR Biomed., vol. 31, no. 10, p. e3832, 2018, doi: 10.1002/nbm.3832. [doi]
7. D. G. J. Heesterbeek et al., “Quantitative in-vivo analysis of biomechanical properties reveals tissue stiffness changes during contraction of the thigh muscles,” in International Society for Magnetic Resonance in Medicine.
8. D. G. J. Heesterbeek et al., “Quasi-static in-vivo elastography from internal displacement information only,” Oct. 14, 2025, arXiv: arXiv:2510.12609. doi: 10.48550/arXiv.2510.12609. [doi]
9. M. Grédiac, F. Pierron, S. Avril, and E. Toussaint, “The Virtual Fields Method for Extracting Constitutive Parameters From Full-Field Measurements: a Review,” Strain, vol. 42, no. 4, pp. 233–253, 2006, doi: 10.1111/j.1475-1305.2006.tb01504.x. [doi]
10. S. A. Maas, B. J. Ellis, G. A. Ateshian, and J. A. Weiss, “FEBio: Finite Elements for Biomechanics,” J. Biomech. Eng., vol. 134, no. 011005, Feb. 2012, doi: 10.1115/1.4005694. [doi]
11. M. Wurm, “A universal and fast method to solve linear systems with correlated coefficients using weighted total least squares,” Meas. Sci. Technol., vol. 33, no. 1, p. 015017, Nov. 2021, doi: 10.1088/1361-6501/ac32ec. [doi]
12. M. H. C. van Riel, T. van Leeuwen, C. A. T. van den Berg, and A. Sbrizzi, “Time-Resolved Reconstruction of Motion, Force, and Stiffness Using Spectro-Dynamic MRI,” IEEE Trans. Comput. Imaging, vol. 9, pp. 917–927, Oct. 2023, doi: 10.1109/TCI.2023.3324757. [doi]
13. M. Froeling, “QMRTools: a Mathematica toolbox for quantitative MRI analysis.,” J. Open Source Softw., vol. 4, no. 38, p. 1204, Jun. 2019, doi: 10.21105/joss.01204. [doi]
14. P. Kennedy et al., “Magnetic resonance elastography (MRE) shows significant reduction of thigh muscle stiffness in healthy older adults,” GeroScience, vol. 42, no. 1, pp. 311–321, Feb. 2020, doi: 10.1007/s11357-019-00147-2. [doi]