Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-03-005 ISMRM Abstract

Glymphatic System Dysfunction Mediates Chemotherapy-Related Central Neurotoxicity in Nasopharyngeal Carcinoma Patients

Primary: Brain Function and fMRI - fMRI Analysis
Secondary: Neuro - Neurofluids
663-03-005 · Glymphatic System Imaging: From Neurofluid Transport to Neurodegeneration · Thursday, 14 May, 1:40 PM–2:35 PM · Digital Posters Row D
Keywords: Glymphatic system Nasopharyngeal carcinoma Induction chemotherapy MRI Central neurotoxicity
Accepted
Daihong Liu 1, Jiahui Zheng2, Junhao Huang2, 菁 张3, Lisha Nie4, Jiuquan Zhang2
1Department of Radiology, Chongqing University Cancer Hospital, Chongqing, China
2Chongqing University Cancer Hospital, Chongqing, China
3Department of Radiology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, ChongQing, China
4GE Healthcare, MR Research China, Beijing, China
Presenting Author: Daihong Liu

Synopsis

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References

1. 1. Wang, J., et al., Cognitive dysfunction in patients with nasopharyngeal carcinoma after induction chemotherapy. Oral Oncol, 2020. 111: p. 104921. PMID: 32763779 [pmid]
2. 2. Holstein-Rønsbo, S., et al., Glymphatic influx and clearance are accelerated by neurovascular coupling. Nat Neurosci, 2023. 26(6): p. 1042-1053. PMID: 37264158 [pmid]
3. 3. Xu, X., et al., Choroid plexus free-water correlates with glymphatic function in Alzheimer's disease. Alzheimers Dement, 2025. 21(5): p. e70239. PMID: 40394891 [pmid]
4. 4. Tanaka, Y., et al., The coupling of global brain activity and cerebrospinal fluid flow as a potential predictive marker of brain amyloid-β accumulation. J Prev Alzheimers Dis, 2025. 12(8): p. 100228. PMID: 40517084 [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/663-03-005