663-01-009 ISMRM Abstract

Flip-Angle Modulated 3D Chemical-Shift-Encoded MRI for T1-Independent, High-SNR PDFF Mapping

Primary: Acquisition & Reconstruction - Quantitative Imaging: chest, abdomen, and pelvis

Secondary: Body - Liver

663-01-009 · Diffusion MRI, Iron Quantification, and Steatosis in Human and Preclinical Studies · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row D

Keywords: Acquisition Methods New Trajectories & Spatial Encoding Methods Liver Quantitative Imaging Proton density fat fraction (PDFF)

Accepted

Jiayi Tang ^1,2, Daiki Tamada¹, Jon-Fredrik Nielsen³, Maxim Zaitsev⁴, Scott B Reeder^1,2,5,6,7, Diego Hernando^1,2

¹Department of Radiology, University of Wisconsin - Madison, Madison, United States of America

²Department of Medical Physics, University of Wisconsin - Madison, Madison, United States of America

³Department of Radiology, University of Michigan, Ann Arbor, United States of America

⁴Division of Medical Physics, Department of Diagnostic and Interventional Radiology, University Medical Center Freiburg, Freiburg, Germany

⁵Department of Biomedical Engineering, University of Wisconsin - Madison, Madison, United States of America

⁶Department of Medicine, University of Wisconsin - Madison, Madison, United States of America

⁷Department of Emergency Medicine, University of Wisconsin - Madison, Madison, United States of America

Presenting Author: Jiayi Tang

Synopsis

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References

1. Starekova J, Hernando D, Pickhardt PJ, Reeder SB. Quantification of Liver Fat Content with CT and MRI: State of the Art. Radiology. 2021;301(2):250-262. doi:10.1148/radiol.2021204288 [doi]

2. Starekova J, Reeder SB. Liver fat quantification: where do we stand? Abdom Radiol N Y. 2020;45(11):3386-3399. doi:10.1007/s00261-020-02783-1 [doi]

3. Panagiotopoulos N, Wolfson T, Harris DT, et al. Proton density fat fraction for diagnosis of metabolic dysfunction–associated steatotic liver disease. Hepatology.:10.1097/HEP.0000000000001318. doi:10.1097/HEP.0000000000001318 [doi]

4. Bray TJ, Chouhan MD, Punwani S, Bainbridge A, Hall-Craggs MA. Fat fraction mapping using magnetic resonance imaging: insight into pathophysiology. Br J Radiol. 2018;91(1089):20170344. doi:10.1259/bjr.20170344 [doi]

5. Liu CY, McKenzie CA, Yu H, Brittain JH, Reeder SB. Fat quantification with IDEAL gradient echo imaging: Correction of bias from T1 and noise. Magn Reson Med. 2007;58(2):354-364. doi:10.1002/mrm.21301 [doi]

6. Kuhn JP, Jahn C, Hernando D, et al. T1 Bias in Chemical Shift-Encoded Liver Fat-Fraction: Role of the Flip Angle. J Magn Reson Imaging. 2013;40(4):875. doi:10.1002/jmri.24457 [doi]

7. Nielsen JF, Noll DC. TOPPE: A framework for rapid prototyping of MR pulse sequences. Magn Reson Med. 2018;79(6):3128-3134. doi:10.1002/mrm.26990 [doi]

8. Layton KJ, Kroboth S, Jia F, et al. Pulseq: A rapid and hardware-independent pulse sequence prototyping framework. Magn Reson Med. 2017;77(4):1544-1552. doi:10.1002/mrm.26235 [doi]

9. Hernando D, Hines CDG, Yu H, Reeder SB. Addressing phase errors in fat-water imaging using a mixed magnitude/complex fitting method. Magn Reson Med. 2012;67(3):638-644. doi:10.1002/mrm.23044 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/663-01-009