Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
304-03-006 ISMRM Abstract

Time-Dependent Diffusion MRI: Unveiling Microstructural Characteristics for Distinguishing Glioblastoma and Brain Metastases

Primary: Neuro - Tumors
Secondary: Diffusion - DWI/DTI/DKI
304-03-006 · Precision MRI: Advanced Quantitative Imaging and Biomarkers for Brain Tumors · Monday, 11 May, 1:50 PM–3:40 PM · Ballroom East
Keywords: Diffusion-Weighted Imaging Glioblastoma Time-dependent diffusion MRI Brain metastases Oscillating gradient spin-echo
Accepted
Shuqi Qiao1, Lin-Feng Yan2, Yi Zhu
1Department of Radiology & Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
2Department of Radiology, Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
Presenting Author: Yi Zhu

Synopsis

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References

1. Ostrom QT, Price M, Neff C, et al. CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2016-2020. Neuro Oncol. 2023;25(12 Suppl 2):iv1-iv99.
2. Schaff LR, Mellinghoff IK. Glioblastoma and Other Primary Brain Malignancies in Adults: A Review. Jama. 2023;329(7):574-87.
3. Johnson DR, Ma DJ, Buckner JC, et al. Conditional probability of long-term survival in glioblastoma: a population-based analysis. Cancer. 2012;118(22):5608-13.
4. Antelo G, Comas S, Casas F, et al. Clinical outcomes and timing on the combination of focal radiation therapy and immunotherapy for the treatment of brain metastases. Front Immunol. 2023;14:1236398.
5. Gore JC, Xu J, Colvin DC, et al. Characterization of tissue structure at varying length scales using temporal diffusion spectroscopy. NMR Biomed. 2010;23(7):745-56.
6. Wu D, Jiang K, Li H, et al. Time-Dependent Diffusion MRI for Quantitative Microstructural Mapping of Prostate Cancer. Radiology. 2022;303(3):578-87.
7. Wang X, Ba R, Huang Y, et al. Time-Dependent Diffusion MRI Helps Predict Molecular Subtypes and Treatment Response to Neoadjuvant Chemotherapy in Breast Cancer. Radiology. 2024;313(1):e240288.
8. Trzpis M, McLaughlin PM, de Leij LM, et al. Epithelial cell adhesion molecule: more than a carcinoma marker and adhesion molecule. Am J Pathol. 2007;171(2):386-95.
9. Oh J, Cha S, Aiken AH, Han ET, et al. Quantitative apparent diffusion coefficients and T2 relaxation times in characterizing contrast enhancing brain tumors and regions of peritumoral edema. J Magn Reson Imaging. 2005;21(6):701-8.
10. Kamimura K, Nakano T, Hasegawa T, et al. Differentiating primary central nervous system lymphoma from glioblastoma by time-dependent diffusion using oscillating gradient. Cancer Imaging. 2023;23(1):114.
11. Kamimura K, Kamimura Y, Nakano T, et al. Differentiating brain metastasis from glioblastoma by time-dependent diffusion MRI. Cancer Imaging. 2023;23(1):75.

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http://echo.ismrm.org/p/ISMRM2026/304-03-006