Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
561-02-015 ISMRM Abstract

Machine Learning with Multiparametric MRI and Clinical Biomarkers for Noninvasive Renal Interstitial Fibrosis Staging

Primary: Body - Kidney
Secondary: Diffusion - IVIM
561-02-015 · Classification and Analysis in the Body · Wednesday, 13 May, 9:15 AM–10:10 AM · Digital Posters Row B
Keywords: Kidney Machine learning MRI Intravoxel incoherent motion (IVIM) Renal interstitial fibrosis
Accepted
Rui Wang 1, Kexin Wang1, Tao Su2
1Radiology Department, Peking University First Hospital, Beijing, China
2Nephrology Department, Peking University First Hospital, Beijing, China
Presenting Author: Rui Wang

Synopsis

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References

1. Chen DQ, Cao G, Chen H, et al. Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan. Nat Commun. 2019;10(1):1476. doi: 10.1038/s41467-019-09329-0. [doi]
2. Zhang Y, Mi X, Zhang Y, et al. Immune checkpoint activity exacerbate renal interstitial fibrosis progression by enhancing PD-L1 expression in renal tubular epithelial cells. Transl Res. 2024;271:52-67. doi: 10.1016/j.trsl.2024.05.004. [doi]
3. Poggio ED, McClelland RL, Blank KN, et al. Systematic Review and Meta-Analysis of Native Kidney Biopsy Complications. Clin J Am Soc Nephrol. 2020;15(11):1595-1602. doi: 10.2215/CJN.04710420. [doi]
4. Charlton JR, Xu Y, Wu T, et al. Magnetic resonance imaging accurately tracks kidney pathology and heterogeneity in the transition from acute kidney injury to chronic kidney disease. Kidney Int. 2021;99(1):173-185. doi: 10.1016/j.kint.2020.08.021. [doi]
5. Srivastava A, Cai X, Lee J, et al. Kidney Functional Magnetic Resonance Imaging and Change in eGFR in Individuals with CKD. Clin J Am Soc Nephrol. 2020;15(6):776-783. doi: 10.2215/CJN.13201019. [doi]
6. Wang R, Lin Z, Yang X, et al. Noninvasive Evaluation of Renal Hypoxia by Multiparametric Functional MRI in Early Diabetic Kidney Disease. J Magn Reson Imaging. 2022;55(2):518-527. doi: 10.1002/jmri.27814. [doi]
7. Mao W, Ding X, Ding Y, et al. Evaluation of interstitial fibrosis in chronic kidney disease by multiparametric functional MRI and histopathologic analysis. Eur Radiol. 2023;33(6):4138-4147. doi: 10.1007/s00330-022-09329-7. [doi]
8. Hua C, Qiu L, Zhou L, et al. Value of multiparametric magnetic resonance imaging for evaluating chronic kidney disease and renal fibrosis. Eur Radiol. 2023;33(8):5211-5221. doi: 10.1007/s00330-023-09674-1. [doi]

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http://echo.ismrm.org/p/ISMRM2026/561-02-015