Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
565-01-006 ISMRM Abstract

Choroid Plexus Cysts on 7T MRI Differentiate NMOSD from MS

Primary: Neuro - Multiple Sclerosis
Secondary: Neuro - Neuroinflammation
565-01-006 · Neuroinflammation: Fluids and Flow · Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row F
Keywords: Multiple Sclerosis 7T MRI Choroid plexus cysts (CPCs) NMOSD
Accepted
Zhiming Zhen 1, Siyao Xu2, Can Xu1, Yunyun Duan2,3, Ying-Hua Chu4, Yi-Cheng Hsu4, Peiyu Huang5, Yaou Liu2,3, Li Gui6, Chen Liu1
17T Magnetic Resonance Translational Medicine Research Center, Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China
2Beijing Tiantan Hospital, Capital Medical University, Beijing, China
3China National Clinical Research Center for Neurological Diseases, Beijing, China
4MR Research Collaboration Team, Shanghai, China
5Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
6Department of Neurology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China
Presenting Author: Zhiming Zhen

Synopsis

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References

1. Kim, Ho Jin, et al. "MRI characteristics of neuromyelitis optica spectrum disorder: an international update." Neurology 84.11 (2015): 1165-1173.
2. Thompson, Alan J., et al. "Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria." The Lancet Neurology 17.2 (2018): 162-173.
3. Xu, Huixin, et al. "The choroid plexus synergizes with immune cells during neuroinflammation." Cell 187.18 (2024): 4946-4963.
4. Saunders, Norman R., et al. "The choroid plexus: a missing link in our understanding of brain development and function." Physiological Reviews 103.1 (2023): 919-956.
5. Lun, Melody P., Edwin S. Monuki, and Maria K. Lehtinen. "Development and functions of the choroid plexus–cerebrospinal fluid system." Nature Reviews Neuroscience 16.8 (2015): 445-457.
6. Müller, Jannis, et al. "Choroid plexus volume in multiple sclerosis vs neuromyelitis optica spectrum disorder: a retrospective, cross-sectional analysis." Neurology: Neuroimmunology & Neuroinflammation 9.3 (2022): e1147.
7. Preziosa, Paolo, et al. "Chronic active lesions and larger choroid plexus explain cognition and fatigue in multiple sclerosis." Neurology: Neuroimmunology & Neuroinflammation 11.2 (2024): e200205.
8. Bergsland, Niels, et al. "Association of choroid plexus inflammation on MRI with clinical disability progression over 5 years in patients with multiple sclerosis." Neurology 100.9 (2023): e911-e920.
9. Levit, Elle, et al. "Choroid plexus volume differentiates MS from its mimics." Multiple Sclerosis Journal 30.8 (2024): 1072-1076.
10. Zhen, Zhiming, et al. "Choroid plexus cysts on 7T MRI: Relationship to aging and neurodegenerative diseases." Alzheimer's & Dementia 21.2 (2025): e14484.
11. Deffner, Felix, et al. "Aquaporin-4 expression in the human choroid plexus." Cellular and Molecular Life Sciences 79.2 (2022): 90.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/565-01-006