Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
301-02-004 ISMRM Abstract

Exploratory Study on Predictive Value of MR Cytometry for Rectal Cancer Histological Differentiation

Primary: Body - Digestive
Secondary: Body - Pelvis
301-02-004 · Advances in Rectum and Pelvis MRI · Monday, 11 May, 8:20 AM–10:10 AM · Hall 1A
Keywords: Rectal cancer Diffusion-Weighted Imaging MR cytometry Microstructural imaging Histological differentiation
Accepted
Qing Zhao1,2, Diwei Shi3,4, Hongxia Zhong1, Zhuo Shi1, Lin Li5, Yueluan Jiang6, Thorsten Feiweier7, Yilan Ji8, Fan Liu9,10, Hua Guo 10, Junzhong Xu11,12, Hongmei Zhang1
1National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
2Shanxi Province Cancer Hospital/ Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, China
3Tsinghua Shenzhen International Graduate School, Tsinghua University, Beijing, China
4Research Institute of Tsinghua University in Shenzhen, China
5Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
6MR Research Collaboration Team, Siemens Healthineers Ltd., Beijing, China
7MR Research and Clinical Translation, Siemens Healthineers AG, Erlangen, Germany
8Beijing National Day School, Beijing, China
9Tsinghua University, Beijing, China
10Center for Biomedical Imaging Research, School of Biomedical Engineering, Tsinghua University, Beijing, China
11Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, United States of America
12Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, United States of America
Presenting Author: Hua Guo

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References

1. Sung H, et al. Colorectal cancer incidence trends in younger versus older adults. J Clin Oncol. 2025;26:51–63.
2. Lișcu H, et al. Therapeutic Management of Locally Advanced Rectal Cancer: Existing and Prospective Approaches. J Clin Med. 2025;14(3).
3. Peng Y, et al. Histological grades of rectal cancer: whole-volume histogram analysis of apparent diffusion coefficient. Quant Imaging Med Surg. 2020;10(1):243–256.
4. Jiang X, Li H, Devan S P, et al. MR cell size imaging with temporal diffusion spectroscopy[J]. Magn Reson Imaging, 2021,77:109-123.
5. Jiang X, et al. Quantification of cell size using temporal diffusion spectroscopy. Magn Reson Med. 2016;75(3):1076–1085.
6. Jiang X, Li H, Xie J, et al. In vivo imaging of cancer cell size and cellularity using temporal diffusion spectroscopy[J]. Magn Reson Med, 2017,78(1):156-164.
7. Jiang X, Devan S P, Xie J, et al. Improving MR cell size imaging by inclusion of transcytolemmal water exchange[J]. NMR Biomed, 2022,35(12):e4799.
8. Xu J, Jiang X, Li H, et al. Magnetic resonance imaging of mean cell size in human breast tumors[J]. Magn Reson Med, 2020,83(6):2002-2014.
9. Shi D, et al. Comprehensive characterization of tumor therapeutic response via simultaneous mapping of cell size, density, and transcytolemmal water exchange. Magn Reson Imaging. 2025;122:110433.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/301-02-004