Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
462-01-004 ISMRM Abstract

Pilot MRI Study for Evaluating Articular Cartilage Injury Using Intra-Articular 17O-Labeled Water in Ex Vivo Porcine Knees

Primary: Musculoskeletal - Cartilage
Secondary: Contrast Mechanisms - Contrast Agents
462-01-004 · Contrast Mechanisms Potpourri Including Registered/Clinical Abstracts · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row C
Accepted
Hiroyuki Kameda 1,2,3, Minami Shimoma4, Taro Fujiwara5, Shotaro Fuchibe6, Taro Igarashi7, Yoshitaka Bito1,4,8, Kazuyuki Minowa9, Kohsuke Kudo1,2,4
1Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, Sappro, Japan
2Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sappro, Japan
3Department of Dental Radiology, Hokkaido University Hospital, Sappro, Japan
4Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, Sappro, Japan
5Department of Radiological Technology, Hokkaido University Hospital, Sappro, Japan
6Science and Technology Organization, GE HealthCare, Hino, Japan
7MR, Imaging Department, GE HealthCare, Hino, Japan
8Hokkaido University, Sappro, Japan
9Faculty of Dental Medicine, Department of Radiology, Hokkaido University, Sappro, Japan
Presenting Author: Hiroyuki Kameda

Synopsis

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References

1. MacKay JW, Low SBL, Smith TO, et al., Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis. Osteoarthritis Cartilage. 2018;26(9):1140-1152.
2. Kameda H, Kinota N, Kato D, et al., Magnetic Resonance Water Tracer Imaging Using 17 O-Labeled Water. Invest Radiol. 2024;59(1):92-103.
3. Hosokawa Y, Onodera T, Homan K, et al., Establishment of a New Qualitative Evaluation Method for Articular Cartilage by Dynamic T2w MRI Using a Novel Contrast Medium as a Water Tracer. Cartilage. 2022;13(3):19476035221111503.
4. https://arxiv.org/abs/2008.06559
5. Carretero-Gómez L, Wiesinger F, Fung M, et al., Rapid and robust quantitative cartilage assessment for the clinical setting: deep learning-enhanced accelerated T2 mapping. Skeletal Radiol. 2025. doi: 10.1007/s00256-025-05034-w. [doi]
6. Sugimori H, Kameda H, Harada T, et al., Quantitative magnetic resonance imaging for evaluating of the cerebrospinal fluid kinetics with 17O-labeled water tracer: A preliminary report. Magn Reson Imaging. 2022 Apr;87:77-85.
7. Cederlund AA, Aspden RM, Walking on water: revisiting the role of water in articular cartilage biomechanics in relation to tissue engineering and regenerative medicine. J R Soc Interface. 2022;19(193):20220364.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/462-01-004