Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
565-01-008 ISMRM Abstract

Choroid plexus alterations link metabolic syndrome severity to cognitive domains: neuroimaging evidence from two cohort

Primary: Neuro - Neuroinflammation
Secondary: Analysis Methods - Data Processing
565-01-008 · Neuroinflammation: Fluids and Flow · Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row F
Accepted
Xinxin Huo 1, TAO Chen2, Zhenyu Cheng3, Boyao Chen1, Fushuai Zhang3, Yiwen Chen1,4, Pengcheng Liang1,4, Nan Zhang4, Yenan Che1, Jiaxiang xin5,6,7, Changhu Liang1, Lingfei Guo1, Meng Li8
1Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
2Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, JINAN, China
3Binzhou Medical University, Yantai City, Shandong Province, China
4Department of Radiograpy, Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
5MR Collaborations, Siemens Healthineers Ltd., Shanghai, China
6Magnetic Resonance Research Collaboration, Siemens Healthineers Ltd, Shanghai, China
7Magnetic Resonance Research Collaboration, Shanghai, China
8Jena University Hospital, Jena, Germany
Presenting Author: Xinxin Huo

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References

1. Wang X, Yang F, Bots ML, Guo WY, Zhao B, Hoes AW, et al. Prevalence of the Metabolic Syndrome Among Employees in Northeast China. Chinese medical journal. 2015;128(15):1989-93. Epub 2015/08/01. doi: 10.4103/0366-6999.161337. PubMed PMID: 26228207; PubMed Central PMCID: PMCPMC4717958. [doi] [pmid]
2. Neeland IJ, Lim S, Tchernof A, Gastaldelli A, Rangaswami J, Ndumele CE, et al. Metabolic syndrome. Nature reviews Disease primers. 2024;10(1):77. Epub 2024/10/18. doi: 10.1038/s41572-024-00563-5. PubMed PMID: 39420195. [doi] [pmid]
3. Yates KF, Sweat V, Yau PL, Turchiano MM, Convit A. Impact of metabolic syndrome on cognition and brain: a selected review of the literature. Arteriosclerosis, thrombosis, and vascular biology. 2012;32(9):2060-7. Epub 2012/08/17. doi: 10.1161/atvbaha.112.252759. PubMed PMID: 22895667; PubMed Central PMCID: PMCPMC3442257. [doi] [pmid]
4. Al-Kuraishy HM, Jabir MS, Albuhadily AK, Al-Gareeb AI, Rafeeq MF. The link between metabolic syndrome and Alzheimer disease: A mutual relationship and long rigorous investigation. Ageing Res Rev. 2023;91:102084. Epub 2023/10/07. doi: 10.1016/j.arr.2023.102084. PubMed PMID: 37802319. [doi] [pmid]
5. Marques F, Sousa JC. The choroid plexus is modulated by various peripheral stimuli: implications to diseases of the central nervous system. Frontiers in cellular neuroscience. 2015;9:136. Epub 2015/08/04. doi: 10.3389/fncel.2015.00136. PubMed PMID: 26236190; PubMed Central PMCID: PMCPMC4394702. [doi] [pmid]
6. Braun M, Iliff JJ. The impact of neurovascular, blood-brain barrier, and glymphatic dysfunction in neurodegenerative and metabolic diseases. International review of neurobiology. 2020;154:413-36. Epub 2020/08/03. doi: 10.1016/bs.irn.2020.02.006. PubMed PMID: 32739013. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/565-01-008