467-03-005 ISMRM Abstract

Quantitative perfusion demonstrates resting myocardial hyperemia in sickle cell anemia patients

Primary: Pediatrics - Cardiovascular

Secondary: Pediatrics - Rare Disease

467-03-005 · Perfusion and Coronary · Tuesday, 12 May, 1:40 PM–2:35 PM · Digital Posters Row H

Keywords: Myocardial T1-mapping Cardiovascular disease Perfusion quantification Sickle Cell Disease Pediatric cardiology

Accepted

Jon A Detterich¹, Sophia X Cui², Rebecca M Stull³, Andrew Cheng³, Jamie K Harrington³, Kelvin Chow^4,5,6,7, Tess E Wallace^{8,9,10,11,12,13,14,15}, Rachel Davids⁹, John C Wood ^1,3,16,17

¹Division of Cardiology, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, United States of America

²Siemens Medical Solutions, Los Angeles, United States of America

³Children's Hospital Los Angeles, Los Angeles, United States of America

⁴Siemens Healthcare Limited, Montreal, Canada

⁵Siemens Medical Solutions USA, Inc., Malvern, United States of America

⁶Cardiovascular MR R&D, Siemens Healthcare Ltd., Calgary, Canada

⁷MR R&D Collaborations, Siemens Medical Solutions USA Inc, Chicago, Illinois, United States of America

⁸Siemens Healthineers, Malvern, United States of America

⁹Siemens Medical Solutions USA, Inc, Chicago, United States of America

¹⁰Boston, US, Siemens Medical Solutions USA, Inc, Chicago, United States of America

¹¹Siemens Medical Solutions, Boston, United States of America

¹²Siemens Medical Solutions USA, Inc., United States of America, United States of America

¹³Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, United States of America

¹⁴MR R&D Collaborations, Siemens Medical Solutions USA, Inc., Chicago, United States of America

¹⁵Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, United States of America

¹⁶USC, Los Angeles, United States of America

¹⁷Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, United States of America

Presenting Author: John C Wood

Synopsis

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References

1. 1. DOI: 10.1182/asheducation-2017.1.423; Gladwin MT. Cardiovascular complications in patients with sickle cell disease. Hematology Am Soc Hematol Educ Program. 2017;2017:423-430. [doi]

2. 2. DOI: 10.1002/ajh.25476; Detterich JA, Kato R, Bush A, Chalacheva P, Ponce D, De Zoysa M, Shah P, Khoo MC, Meiselman HJ, Coates TD and Wood JC. Sickle cell microvascular paradox-oxygen supply-demand mismatch. Am J Hematol. 2019;94:678-688. [doi]

3. 3. PMCID: PMC2594344; Nahavandi M, Millis RM, Tavakkoli F, Wyche MQ, Perlin E, Winter WP and Castro O. Arterialization of peripheral venous blood in sickle cell disease. J Natl Med Assoc. 2002;94:320-6.

4. 4. DOI: 10.1186/s12968-017-0355-5; Kellman P, Hansen MS, Nielles-Vallespin S, Nickander J, Themudo R, Ugander M and Xue H. Myocardial perfusion cardiovascular magnetic resonance: optimized dual sequence and reconstruction for quantification. J Cardiovasc Magn Reson. 2017;19:43. [doi]

5. 5. DOI: 10.1002/mrm.27954; Xue H, Brown LAE, Nielles-Vallespin S, Plein S and Kellman P. Automatic in-line quantitative myocardial perfusion mapping: Processing algorithm and implementation. Magn Reson Med. 2020;83:712-730. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/467-03-005