Justin R Singer1, Elena I Ivleva2, Kimberly L Chan 1
1University of Texas Southwestern Medical Center, Dallas, United States of America
2Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, United States of America
Presenting Author: Kimberly L Chan
Synopsis
Motivation:
Goals:
Approach:
Results:
Full abstract & presentation
The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.
Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.
To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.
1. (1) Sonnay, S.; Gruetter, R.; Duarte, J. M. N. How Energy Metabolism Supports Cerebral Function: Insights from 13C Magnetic Resonance Studies In vivo. Frontiers in Neuroscience 2017, Volume 11 - 2017, Review. DOI: 10.3389/fnins.2017.00288. [doi]
2. (2) Bjorklund, G.; Peana, M.; Maes, M.; Dadar, M.; Severin, B. The glutathione system in Parkinson’s disease and its progression. Neuroscience & Biobehavioral Reviews 2020. DOI: 10.1016/j.neubiorev.2020.10.004. [doi]
3. (3) Chen, J. J.; Thiyagarajah, M.; Song, J.; Chen, C.; Herrmann, N.; Gallagher, D.; Rapoport, M. J.; Black, S. E.; Ramirez, J.; Andreazza, A. C.; et al. Altered central and blood glutathione in Alzheimer's disease and mild cognitive impairment: a meta-analysis. Alzheimers Res Ther 2022, 14 (1), 23. DOI: 10.1186/s13195-022-00961-5 From NLM. [doi]
4. (4) Paul, B. D.; Sbodio, J. I.; Snyder, S. H. Mutant Huntingtin Derails Cysteine Metabolism in Huntington’s Disease at Both Transcriptional and Post-Translational Levels. Antioxidants 2022, 11 (8), 1470.
5. (5) Brady, R. O., Jr.; McCarthy, J. M.; Prescot, A. P.; Jensen, J. E.; Cooper, A. J.; Cohen, B. M.; Renshaw, P. F.; Ongür, D. Brain gamma-aminobutyric acid (GABA) abnormalities in bipolar disorder. Bipolar Disord 2013, 15 (4), 434-439. DOI: 10.1111/bdi.12074 From NLM. [doi]
6. (6) de Jonge, J. C.; Vinkers, C. H.; Hulshoff Pol, H. E.; Marsman, A. GABAergic Mechanisms in Schizophrenia: Linking Postmortem and In Vivo Studies. Front Psychiatry 2017, 8, 118. DOI: 10.3389/fpsyt.2017.00118 From NLM. [doi]
7. (7) Sarawagi, A.; Soni, N. D.; Patel, A. B. Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder. Frontiers in Psychiatry 2021, Volume 12 - 2021, Review. DOI: 10.3389/fpsyt.2021.637863. [doi]
8. (8) Brancati, G. E.; Rawas, C.; Ghestem, A.; Bernard, C.; Ivanov, A. I. Spatio-temporal heterogeneity in hippocampal metabolism in control and epilepsy conditions. Proceedings of the National Academy of Sciences 2021, 118 (11), e2013972118. DOI: 10.1073/pnas.2013972118 (acccessed 2025/10/19). [doi]
9. (9) Angeli, P. A.; DiNicola, L. M.; Saadon-Grosman, N.; Eldaief, M. C.; Buckner, R. L. Specialization of the human hippocampal long axis revisited. Proceedings of the National Academy of Sciences 2025, 122 (3), e2422083122. DOI: 10.1073/pnas.2422083122 (acccessed 2025/10/19). [doi]
10. (10) Nadel, L.; Hoscheidt, S.; Ryan, L. Spatial Cognition and the Hippocampus: The Anterior–Posterior Axis. Journal of Cognitive Neuroscience 2013, 25, 22-28. DOI: 10.1162/jocn_a_00313. [doi]
11. (11) Simpson, R.; Devenyi, G. A.; Jezzard, P.; Hennessy, T. J.; Near, J. Advanced processing and simulation of MRS data using the FID appliance (FID-A)-An open source, MATLAB-based toolkit. Magn Reson Med 2017, 77 (1), 23-33. DOI: 10.1002/mrm.26091 From NLM. [doi]
12. (12) Chan, K. L.; Hock, A.; Edden, R. A. E.; MacMillan, E. L.; Henning, A. Improved prospective frequency correction for macromolecule-suppressed GABA editing with metabolite cycling at 3T. Magnetic Resonance in Medicine 2021, 86 (6), 2945-2956. DOI: https://doi.org/10.1002/mrm.28950. [doi]
13. (13) Edden, R. A.; Puts, N. A.; Harris, A. D.; Barker, P. B.; Evans, C. J. Gannet: A batch-processing tool for the quantitative analysis of gamma-aminobutyric acid–edited MR spectroscopy spectra. J Magn Reson Imaging 2014, 40 (6), 1445-1452. DOI: 10.1002/jmri.24478 From NLM. [doi]
14. (14) Borbath, T.; Murali-Manohar, S.; Dorst, J.; Wright, A. M.; Henning, A. ProFit-1D-A 1D fitting software and open-source validation data sets. Magn Reson Med 2021, 86 (6), 2910-2929. DOI: 10.1002/mrm.28941 From NLM. [doi]
15. (15) Juchem, C.; Cudalbu, C.; de Graaf, R. A.; Gruetter, R.; Henning, A.; Hetherington, H. P.; Boer, V. O. B0 shimming for in vivo magnetic resonance spectroscopy: Experts' consensus recommendations. NMR in Biomedicine 2021, 34 (5), e4350. DOI: https://doi.org/10.1002/nbm.4350. [doi]
16. (16) King, K. G.; Glodzik, L.; Liu, S.; Babb, J. S.; de Leon, M. J.; Gonen, O. Anteroposterior hippocampal metabolic heterogeneity: three-dimensional multivoxel proton 1H MR spectroscopic imaging--initial findings. Radiology 2008, 249 (1), 242-250. DOI: 10.1148/radiol.2491071500 From NLM. [doi]
17. (17) Beletskiy, A.; Positselskaya, E.; Vinarskaya, A. K.; Spivak, Y. S.; Dobryakova, Y. V.; Tyulenev, I.; Markevich, V. A.; Bolshakov, A. P. Detailed Analysis of Dorsal-Ventral Gradients of Gene Expression in the Hippocampus of Adult Rats. Int J Mol Sci 2022, 23 (17). DOI: 10.3390/ijms23179948 From NLM. [doi]
18. (18) Robert, K.; Vialard, F.; Thiery, E.; Toyama, K.; Sinet, P. M.; Janel, N.; London, J. Expression of the cystathionine beta synthase (CBS) gene during mouse development and immunolocalization in adult brain. J Histochem Cytochem 2003, 51 (3), 363-371. DOI: 10.1177/002215540305100311 From NLM. [doi]
19. (19) Vitvitsky, V.; Thomas, M.; Ghorpade, A.; Gendelman, H. E.; Banerjee, R. A Functional Transsulfuration Pathway in the Brain Links to Glutathione Homeostasis *. Journal of Biological Chemistry 2006, 281 (47), 35785-35793. DOI: 10.1074/jbc.M602799200 (acccessed 2025/10/27). [doi]