Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
665-03-003 ISMRM Abstract

Subvoxel Quantitative Susceptibility Decomposition Reveals Distinct Paramagnetic and Diamagnetic Alterations in PD

Primary: Neuro - fMRI & Neuromodulation
Secondary: Analysis Methods - fMRI Analysis
665-03-003 · fMRI: Applications in Neurology and Psychiatry III · Thursday, 14 May, 1:40 PM–2:35 PM · Digital Posters Row F
Keywords: Parkinson's Disease Quantitative Susceptibility mapping
Accepted
liu di 1, Yueluan Jiang2, Boyu Chen3
1Department of radiology, The First Hospital of China Medical University, Shenyang, China
2MR Research Collaboration Team, Siemens Healthineers Ltd., Beijing, China
3Radiology, The First Hospital of China Medical University, Shenyang, China
Presenting Author: liu di

Synopsis

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References

1. Yan S, Lu J, Duan B, Zhu H, Liu D, Li L, Qin Y, Li Y, Zhu W. Quantitative susceptibility mapping of multiple system atrophy and Parkinson's disease correlates with neurotransmitter reference maps. Neurobiol Dis. 2024 Aug;198:106549. doi: 10.1016/j.nbd.2024.106549. Epub 2024 Jun 1. PMID: 38830476. [doi] [pmid]
2. Jankovic J. Parkinson’s disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry.2008;79(4):368–376. doi:10.1136/jnnp.2007.131045 [PubMed: 18344392] [doi] [pmid]
3. Poewe W, Stankovic I, Halliday G, Meissner WG, Wenning GK, Pellecchia MT, Seppi K, Palma JA, Kaufmann H. Multiple system atrophy. Nat Rev Dis Primers. 2022 Aug 25;8(1):56. doi: 10.1038/s41572-022-00382-6. PMID: 36008429. [doi] [pmid]
4. Zeng W, Cai J, Zhang L, Peng Q. Iron Deposition in Parkinson's Disease: A Mini-Review. Cell Mol Neurobiol. 2024 Feb 23;44(1):26. doi: 10.1007/s10571-024-01459-4. PMID: 38393383; PMCID: PMC10891198. [doi] [pmid]
5. Chen J, Gong NJ, Chaim KT, Otaduy MCG, Liu C. Decompose quantitative susceptibility mapping (QSM) to sub-voxel diamagnetic and paramagnetic components based on gradient-echo MRI data. Neuroimage. 2021 Nov 15;242:118477. doi: 10.1016/j.neuroimage.2021.118477. Epub 2021 Aug 14. PMID: 34403742; PMCID: PMC8720043. [doi] [pmid]
6. Kim M, Ji S, Kim J, Min K, Jeong H, Youn J, Kim T, Jang J, Bilgic B, Shin HG, Lee J. χ-sepnet: Deep Neural Network for Magnetic Susceptibility Source Separation. Hum Brain Mapp. 2025 Feb 1;46(2):e70136. doi: 10.1002/hbm.70136. PMID: 39835664; PMCID: PMC11748151. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/665-03-003