Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
466-06-010 ISMRM Abstract

Mid Field (0.6T) Magnetic Resonance Elastography of the Lung: Technical Feasibility

Accepted
Emi Hojo 1, Richard Ehman1, Yogesh k Mariappan2, Spencer Waddle1,3, Yuan Le1, Sandeep Ganji1,3, Chi Wan Koo1, Kiaran P McGee1
1Department of Radiology, Mayo Clinic, Rochester, United States of America
2Philips Healthcare, Bengaluru, India
3MR Clinical Science, Philips North America, MN, United States of America
Presenting Author: Emi Hojo

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Kalchiem-Dekel O, Galvin JR, Burke AP, Atamas SP, Todd NW. Interstitial Lung Disease and Pulmonary Fibrosis: A Practical Approach for General Medicine Physicians with Focus on the Medical History. J Clin Med. Nov 24 2018;7(12)doi:10.3390/jcm7120476 [doi]
2. Suki B, Stamenović D, Hubmayr R. Lung parenchymal mechanics. Compr Physiol. Jul 2011;1(3):1317-51. doi:10.1002/cphy.c100033 [doi]
3. Che B, Ni K, Liu Z, Liu L, Luo M, Deng L. Mechanical biomarkers in respiratory diseases: From mechanobiology to mechanomedicine. Biophysics Reviews. 2025;6(3) https://doi.org/10.1063/5.0266508 [doi]
4. Bernstein EJ, Jaafar S, Assassi S, et al. Performance Characteristics of Pulmonary Function Tests for the Detection of Interstitial Lung Disease in Adults With Early Diffuse Cutaneous Systemic Sclerosis. Arthritis Rheumatol. Nov 2020;72(11):1892-1896. doi:10.1002/art.41415 [doi]
5. Ciancio N, Pavone M, Torrisi SE, et al. Contribution of pulmonary function tests (PFTs) to the diagnosis and follow up of connective tissue diseases. Multidisciplinary Respiratory Medicine. 2019/05/15 2019;14(1):17. doi:10.1186/s40248-019-0179-2 [doi]
6. Khanna D, Distler O, Cottin V, et al. Diagnosis and monitoring of systemic sclerosis-associated interstitial lung disease using high-resolution computed tomography. J Scleroderma Relat Disord. Oct 2022;7(3):168-178. doi:10.1177/23971983211064463 [doi]
7. Muthupillai R, Lomas DJ, Rossman PJ, Greenleaf JF, Manduca A, Ehman RL. Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. Science. Sep 29 1995;269(5232):1854-7. doi:10.1126/science.7569924 [doi]
8. Ehman RL. Magnetic resonance elastography: from invention to standard of care. Abdom Radiol (NY). Sep 2022;47(9):3028-3036. doi:10.1007/s00261-022-03597-z [doi]
9. Mariappan YK, Glaser KJ, Levin DL, et al. Estimation of the absolute shear stiffness of human lung parenchyma using (1) H spin echo, echo planar MR elastography. J Magn Reson Imaging. Nov 2014;40(5):1230-7. doi:10.1002/jmri.24479 [doi]
10. Marinelli JP, Levin DL, Vassallo R, et al. Quantitative assessment of lung stiffness in patients with interstitial lung disease using MR elastography. Journal of Magnetic Resonance Imaging. 2017/08/01 2017;46(2):365-374. doi:https://doi.org/10.1002/jmri.25579 [doi]
11. Bensamoun SF, McGee KP, Chakouch M, Pouletaut P, Charleux F. Monitoring of lung stiffness for long-COVID patients using magnetic resonance elastography (MRE). Magn Reson Imaging. Jan 2025;115:110269. doi:10.1016/j.mri.2024.110269 [doi]
12. Bensamoun SF, McGee KP, Chakouch M, Pouletaut P, Charleux F. Quantification of Lung Stiffness Using Magnetic Resonance Elastography (MRE): Clinical Validation for Smokers. IEEE Trans Biomed Eng. Mar 20 2025;Ppdoi:10.1109/tbme.2025.3553375 [doi]
13. Venkatesh SK, Yin M, Glockner JF, et al. MR elastography of liver tumors: preliminary results. AJR Am J Roentgenol. Jun 2008;190(6):1534-40. doi:10.2214/ajr.07.3123 [doi]
14. Campbell-Washburn AE. 2019 American Thoracic Society BEAR Cage Winning Proposal: Lung Imaging Using High-Performance Low-Field Magnetic Resonance Imaging. Am J Respir Crit Care Med. Jun 1 2020;201(11):1333-1336. doi:10.1164/rccm.201912-2505ED [doi]
15. Tian Y, Nayak KS. New clinical opportunities of low-field MRI: heart, lung, body, and musculoskeletal. Magma. Feb 2024;37(1):1-14. doi:10.1007/s10334-023-01123-w [doi]
16. Rump J, Klatt D, Braun J, Warmuth C, Sack I. Fractional encoding of harmonic motions in MR elastography. Magn Reson Med. Feb 2007;57(2):388-95. doi:10.1002/mrm.21152 [doi]
17. Silva AM, Grimm RC, Glaser KJ, et al. Magnetic resonance elastography: evaluation of new inversion algorithm and quantitative analysis method. Abdom Imaging. Apr 2015;40(4):810-7. doi:10.1007/s00261-015-0372-5 [doi]
18. McGee KP, Lake D, Mariappan Y, et al. Calculation of shear stiffness in noise dominated magnetic resonance elastography data based on principal frequency estimation. Phys Med Biol. Jul 21 2011;56(14):4291-309. doi:10.1088/0031-9155/56/14/006 [doi]
19. Mariappan YK, Kolipaka A, Manduca A, et al. Magnetic resonance elastography of the lung parenchyma in an in situ porcine model with a noninvasive mechanical driver: correlation of shear stiffness with trans-respiratory system pressures. Magn Reson Med. Jan 2012;67(1):210-7. doi:10.1002/mrm.22976 [doi]
20. Mariappan YK, Glaser KJ, Hubmayr RD, Manduca A, Ehman RL, McGee KP. MR elastography of human lung parenchyma: Technical development, theoretical modeling and in vivo validation. Journal of Magnetic Resonance Imaging. 2011/06/01 2011;33(6):1351-1361. doi:https://doi.org/10.1002/jmri.22550 [doi]
21. LoMauro A, Aliverti A. Sex differences in respiratory function. Breathe (Sheff). Jun 2018;14(2):131-140. doi:10.1183/20734735.000318 [doi]
22. Fakhouri F, Kannengiesser S, Pfeuffer J, Gokun Y, Kolipaka A. Free-breathing MR elastography of the lungs: An in vivo study. Magn Reson Med. Jan 2022;87(1):236-248. doi:10.1002/mrm.28986 [doi]
23. Talaminos Barroso A, Márquez Martín E, Roa Romero LM, Ortega Ruiz F. Factors Affecting Lung Function: A Review of the Literature. 10.1016/j.arbr.2018.04.003. Archivos de Bronconeumología. 2018;54(6):327-332. doi:10.1016/j.arbr.2018.04.003 [doi]
24. Rutting S, Chapman DG, Badal T, et al. Higher body mass index is associated with increased lung stiffness and less airway obstruction in individuals with asthma and fixed airflow obstruction. ERJ Open Res. Jan 2021;7(1)doi:10.1183/23120541.00336-2020 [doi]

Cite this abstract