Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
560-04-006 ISMRM Abstract

Free-Running 3D Cardiac T1 Mapping using Look-Locker and Variable Flip Angle Imaging with Low-Rank Modeling

Primary: Cardiovascular - Myocardium
Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
560-04-006 · Automated Cardiovascular MRI · Wednesday, 13 May, 2:35 PM–3:30 PM · Digital Posters Row A
Keywords: T1 Mapping Variable flip angle Cardiac Low-rank reconstruction 3d
Accepted
Paul K Han1,2, Thibault Marin1,2, Wonil Lee1,2, Didi Chi1,2, Guodong Weng 1,2,3,4, Ismaël Mounime1,2,5, Jaehun Lee1,2, John Stendahl1,6, Georges El Fakhri1,2, Chao Ma1,2
1Yale Biomedical Imaging Institute, Yale University School of Medicine, New Haven, United States of America
2Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, United States of America
3Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland
4Translational Imaging Center, sitem-insel, Bern, Switzerland
5LTCI, Télécom Paris, Institut Polytechnique de Paris, France
6Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, United States of America
Presenting Author: Guodong Weng

Synopsis

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References

1. Kramer, C. M. et al. Standardized cardiovascular magnetic resonance imaging (CMR) protocols: 2020 update. J Cardiovasc Magn Reson 22, 17 (2020). https://doi.org:10.1186/s12968-020-00607-1.
2. Haaf, P. et al. Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: A comprehensive review. Journal of Cardiovascular Magnetic Resonance 18, 1-12 (2016). https://doi.org:10.1186/s12968-016-0308-4.
3. D. R. Messroghli et al., "Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2 and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imagin," Journal of Cardiovascular Magnetic Resonance, vol. 19, no. 1, pp. 1-24, 2017, doi: 10.1186/s12968-017-0389-8. [doi]
4. Messroghli, D. R. et al. Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2 and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imagin. Journal of Cardiovascular Magnetic Resonance 19, 1-24 (2017). https://doi.org:10.1186/s12968-017-0389-8.
5. Qi, H. et al. Free-running 3D whole heart myocardial T1 mapping with isotropic spatial resolution. Magnetic Resonance in Medicine 82, 1331-1342 (2019). https://doi.org:10.1002/mrm.27811.
6. Wang, X. et al. Free-breathing myocardial T(1) mapping using inversion-recovery radial FLASH and motion-resolved model-based reconstruction. Magn Reson Med 89, 1368-1384 (2023). https://doi.org:10.1002/mrm.29521.
7. Zhou, R. et al. Dual-excitation flip-angle simultaneous cine and T(1) mapping using spiral acquisition with respiratory and cardiac self-gating. Magn Reson Med 86, 82-96 (2021). https://doi.org:10.1002/mrm.28675.
8. Hamilton, J. I., Jiang, Y., Eck, B., Griswold, M. & Seiberlich, N. Cardiac cine magnetic resonance fingerprinting for combined ejection fraction, T1 and T2 quantification. NMR in Biomedicine 33, 1-17 (2020). https://doi.org:10.1002/nbm.4323.
9. Jaubert, O. et al. Free-running cardiac magnetic resonance fingerprinting: Joint T1/T2 map and Cine imaging. Magnetic Resonance Imaging 68, 173-182 (2020). https://doi.org:10.1016/j.mri.2020.02.005.
10. Christodoulou, A. G. et al. Magnetic resonance multitasking for motion-resolved quantitative cardiovascular imaging. Nature Biomedical Engineering 2, 215-226 (2018). https://doi.org:10.1038/s41551-018-0217-y.
11. Shaw, J. L. et al. Free-breathing, non-ECG, continuous myocardial T1 mapping with cardiovascular magnetic resonance multitasking. Magnetic Resonance in Medicine 81, 2450-2463 (2019). https://doi.org:10.1002/mrm.27574.
12. Serry F.M., Ma S., Mao X., Han F., Xie Y., Han H., Li D., Christodoulou A.G. Dual flip‐angle IR‐FLASH with spin history mapping for B1+ corrected T1 mapping: Application to T1 cardiovascular magnetic resonance multitasking. Magnetic resonance in medicine. 2021 Dec;86(6):3182-91.
13. Phair, A., Cruz, G., Qi, H., Botnar, R. M. & Prieto, C. Free-running 3D whole-heart T(1) and T(2) mapping and cine MRI using low-rank reconstruction with non-rigid cardiac motion correction. Magn Reson Med 89, 217-232 (2023). https://doi.org:10.1002/mrm.29449.
14. Han, P. K. et al. Free‐breathing 3D cardiac T1 mapping with transmit B1 correction at 3T. Magnetic Resonance in Medicine 87, 1832-1845 (2022).
15. Look D.C. and Locker D.R. Time saving in measurement of NMR and EPR relaxation times. Review of scientific instruments, 41(2), 250 (1970).
16. Deichmann R. and Haase A. Quantification of T1 values by SNAPSHOT-FLASH NMR imaging. Journal of Magnetic Resonance (1969). 1992 Feb 15;96(3):608-12.
17. Fram E.K., Herfkens R.J., Johnson G.A., Glover G.H., Karis J.P., Shimakawa A., Perkins T.G., Pelc N.J. Rapid calculation of T1 using variable flip angle gradient refocused imaging. Magnetic resonance imaging. Jan 1;5(3):201-8 (1987).
18. Yarnykh, V. L. Actual flip-angle imaging in the pulsed steady state: a method for rapid three-dimensional mapping of the transmitted radiofrequency field. Magn Reson Med 57, 192-200 (2007). https://doi.org:10.1002/mrm.21120.
19. Yarnykh, V. L. Optimal radiofrequency and gradient spoiling for improved accuracy of T1 and B1 measurements using fast steady-state techniques. Magn Reson Med 63, 1610-1626 (2010). https://doi.org:10.1002/mrm.22394.
20. Lee, W. et al. Free-breathing 3D cardiac extracellular volume (ECV) mapping using a linear tangent space alignment (LTSA) model. Magnetic Resonance in Medicine (2024). https://doi.org:10.1002/mrm.30284.

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http://echo.ismrm.org/p/ISMRM2026/560-04-006