Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-04-007 ISMRM Abstract

Characterization of White Matter Hyperintensities and Penumbras across Different Fazekas Scales

Primary: Neuro - White Matter
Secondary: Neuro - Stroke and Cerebrovascular Disorders
663-04-007 · Cerebral Small Vessel Disease: Network, Glymphatic, and Blood Flow · Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row D
Keywords: White Matter Hypointensities Fazekas Penumbras
Accepted
xin wang 1,2, Yue-Qing Yang3, De-Yu Gao4, Ben Wang4, Li-Na Feng2, Su-Jie Wang5, Min-Ying Su1,6, Yu Wang2
1Department of Radiological Sciences, University of California, Irvine, United States of America
2Department of Radiology, Tangshan Gongren Hospital, Tangshan City, Hebei Province, Tangshan, China
3Tangshan Gongren Hospital, Tangshan City, Hebei Province, Tangshan, China
4North China University of Technology, Tangshan City, Hebei Province, Tangshan, China
5Department of Neurology, Tangshan Gongren Hospital, Tangshan City, Hebei Province, Tangshan, China
6Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan
Presenting Author: xin wang

Synopsis

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References

1. [1] Chojdak-Lukasiewicz J, Dziadkowiak E, Zimny A, Paradowski B. Cerebral small vessel disease: A review. Adv Clin Exp Med. 2021;30(3):349-56. DOI: 10.17219/acem/131216 [doi]
2. Lisa C Silbert NER, Justin Hurworth, David Lahna, Victoria Krajbich, Daniel L Schwartz, Randy L Woltjer. Pathological features of the 7T post-mortem MRIwhite matter hyperintensity penumbra. Alzheimer's & Dementia. 2021;17(3):e052304. DOI: 10.1002/alz.052304 [doi]
3. Voorter PHM, Stringer MS, van Dinther M, Kerkhofs D, Dewenter A, Blair GW, et al. Heterogeneity and Penumbra of White Matter Hyperintensities in Small Vessel Diseases Determined by Quantitative MRI. Stroke. 2025;56(1):128-37. DOI: 10.1161/STROKEAHA.124.047910 [doi]
4. Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA. MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR Am J Roentgenol. 1987;149(2):351-6. DOI: 10.2214/ajr.149.2.351 [doi]
5. Wang X, Wang Y, Gao D, Zhao Z, Wang H, Wang S, et al. Characterizing the penumbras of white matter hyperintensities in patients with cerebral small vessel disease. Jpn J Radiol. 2023;41(9):928-37. DOI: 10.1007/s11604-023-01419-w [doi]
6. Tubi MA, Feingold FW, Kothapalli D, Hare ET, King KS, Thompson PM, et al. White matter hyperintensities and their relationship to cognition: Effects of segmentation algorithm. Neuroimage. 2020;206:116327. DOI: 10.1016/j.neuroimage.2019.116327 [doi]
7. Li H, Jacob MA, Cai M, Kessels RPC, Norris DG, Duering M, et al. Perivascular Spaces, Diffusivity Along Perivascular Spaces, and Free Water in Cerebral Small Vessel Disease. Neurology. 2024;102(9):e209306. DOI: 10.1212/WNL.0000000000209306 [doi]

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http://echo.ismrm.org/p/ISMRM2026/663-04-007