Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
561-05-011 ISMRM Abstract

Placental blood-flow velocity quantification from diffusion MRI in Normal and Complicated Pregnancy

Primary: Body - Placenta
Secondary: Diffusion - Diffusion Modeling
561-05-011 · Advanced MR Techniques in Cervical, Genital, Placental, and Fetal Disorders · Wednesday, 13 May, 4:00 PM–4:55 PM · Digital Posters Row B
Keywords: Placenta Diffusion MRI Perfusion abnormalities Blood velocity Machine learning (ML)
Accepted
Zhuangjian Yang 1, Diana M Cruz De Oliveira2, Sonja Soskic3, Lisa Story4, Jo V Hajnal5,6, Jana Hutter5,6,7, Shipley Rebecca2, Daniel C Alexander1, Paddy Slator8,9
1Hawkes Institute, Department of Computer Science, University College London, London, United Kingdom
2Department of Mechanical Engineering, University College London, London, United Kingdom
3Hawkes Institute, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom
4Department of Women and Children's Health, School of Life Course Sciences, King's College London, London, United Kingdom
5Research Department of Imaging Physics and Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom
6Research Department of Early Life Imaging Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom
7Smart Imaging Lab, Radiological Institute, University Hospital Erlangen (UKER), Erlangen, Germany
8School of Computer Science and Informatics, Cardiff University, Cardiff, United Kingdom
9Cardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology, Cardiff University, Cardiff, United Kingdom
Presenting Author: Zhuangjian Yang

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References

1. Chappell LC, Cluver CA, Kingdom J, Tong S. Pre-eclampsia. The Lancet 2021;398(10297):341-354.
2. Sinding M, Peters DA, Frøkjær JB, Christiansen OB, Petersen A, Uldbjerg N, Sørensen A. Placental magnetic resonance imaging T2* measurements in normal pregnancies and in those complicated by fetal growth restriction. Ultrasound in Obstetrics & Gynecology 2016;47(6):748-754.
3. Collins SL, Stevenson GN, Noble JA, Impey L. Developmental changes in spiral artery blood flow in the human placenta observed with colour Doppler ultrasonography. Placenta 2012;33(10):782-787.
4. Cnossen JS, Morris RK, ter Riet G, Mol BWJ, van der Post JAM, Coomarasamy A, Zwinderman AH, Robson SC, Bindels PJE, Kleijnen J, Khan KS. Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis. Canadian Medical Association Journal 2008;178(6):701.
5. Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 1986;161(2):401-407.
6. Voronova AK, Grigoriou A, Bernatowicz K, Simonetti S, Serna G, Roson N, Escobar M, Vieito M, Nuciforo P, Toledo R, Garralda E, Fieremans E, Novikov DS, Palombo M, Perez-Lopez R, Grussu F. SpinFlowSim: A blood flow simulation framework for histology-informed diffusion MRI microvasculature mapping in cancer. Medical Image Analysis 2025;102:103531.
7. Powell E, Parker GJM, Palombo M. VASAL: A Vascular Substrate Algorithm to Generate Microvascular Network Phantoms. bioRxiv 2025:2025.2009.2005.674056.
8. Yang, Z., de Oliveira, D.C., Kerkelä, L., Palombo, M., Powell, E., Parker, C.S., Cromb, D., Story, L., Counsell, S., Payette, K., Hajnal, J.V., Hutter, J., Shipley, R.J., Alexander, D.C., & Slator, P.J. Placental blood-flow velocity quantification from diffusion MRI. Proceedings of the ISMRM Annual Meeting, Abstract No. 0166, 2025.
9. Slator PJ, Hutter J, Ianus A, Panagiotaki E, Rutherford MA, Hajnal JV, Alexander DC. A Framework for Calculating Time-Efficient Diffusion MRI Protocols for Anisotropic IVIM and An Application in the Placenta. In: Bonet-Carne E, Grussu F, Ning L, Sepehrband F, Tax CMW, editors2019 2019//; Cham. Springer International Publishing. p 251-263.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/561-05-011