Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
666-01-012 ISMRM Abstract

Coil Combination of Hyperpolarized C-13 Imaging by Estimating L2-Optimized Sensitivity Maps

Primary: Contrast Mechanisms - Hyperpolarized MR (Non-Gas)
Secondary: Acquisition & Reconstruction - Image Reconstruction: Non-AI
666-01-012 · Hyperpolarization: Novel Methods · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row G
Keywords: X-nuclei Hyperpolarized 13C MRI Coil combination Signal-to-noise-ratio
Accepted
Anna C Bennett Haller1,2, Minjie Zhu 1, Peder Larson1, Jeremy W Gordon1, Nicholas Dwork3
1Department of Radiology and Biomedical Imaging, University Of California, San Francisco (UCSF), United States of America
2UCSF-UC Berkeley Graduate Program in Bioengineering, United States of America
3University of Colorado Anschutz, Aurora, United States of America
Presenting Author: Minjie Zhu

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References

1. Zhu Z, Zhu X, Ohliger MA, et al. Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies. J Magn Reson. 2019;301:73-79. doi:10.1016/j.jmr.2019.01.015 [doi]
2. Crane JC, Gordon JW, Chen H, et al. Hyperpolarized 13 C MRI data acquisition and analysis in prostate and brain at University of California, San Francisco. NMR Biomed. 2021;34(5). doi:10.1002/nbm.4280 [doi]
3. Gordon JW, Autry AW, Tang S, et al. A variable resolution approach for improved acquisition of hyperpolarized13 C metabolic MRI. Magn Reson Med. 2020;84(6):2943-2952. doi:10.1002/mrm.28421 [doi]
4. Lee PM, Chen H, Gordon JW, et al. Whole‐Abdomen Metabolic Imaging of Healthy Volunteers Using Hyperpolarized [ 1‐13 C ]pyruvate MRI. J Magn Reson Imaging. 2022;56(6):1792-1806. doi:10.1002/jmri.28196 [doi]
5. Tang S, Meng MV, Slater JB, et al. Metabolic imaging with hyperpolarized13 C pyruvate magnetic resonance imaging in patients with renal tumors—Initial experience. Cancer. 2021;127(15):2693-2704. doi:10.1002/cncr.33554 [doi]
6. Dwork N, Gordon JW, Tang S, Larson PEZ. Estimating Sensitivity Maps for X-Nuclei Magnetic Resonance Spectroscopic Imaging. arXiv. Preprint posted online 2025. doi:10.48550/ARXIV.2507.18850 [doi]
7. Larson PEZ, Tang S, Liu X, et al. Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate CMR evaluated in an oral glucose challenge. J Cardiovasc Magn Reson. 2023;25(1):77. doi:10.1186/s12968-023-00972-7 [doi]
8. Autry AW, Vaziri S, Gordon JW, et al. Advanced Hyperpolarized 13C Metabolic Imaging Protocol for Patients with Gliomas: A Comprehensive Multimodal MRI Approach. Cancers. 2024;16(2):354. doi:10.3390/cancers16020354 [doi]
9. Gordon JW, Chen H, Nickles T, et al. Hyperpolarized 13 C Metabolic MRI of Patients with Pancreatic Ductal Adenocarcinoma. J Magn Reson Imaging. 2024;60(2):741-749. doi:10.1002/jmri.29162 [doi]
10. Kellman P, McVeigh ER. Image reconstruction in SNR units: A general method for SNR measurement†. Magn Reson Med. 2005;54(6):1439-1447. doi:10.1002/mrm.20713 [doi]

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http://echo.ismrm.org/p/ISMRM2026/666-01-012