Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
462-04-009 ISMRM Abstract

Differential Effects of T2DM and HFD on Rat Body Tissues: A Quantitative mDixon-Quant Evaluation

Primary: Preclinical Animal & in vitro MR - Small Animals
Secondary: Musculoskeletal - Other Musculoskeletal
462-04-009 · Body, Cardiovascular, and Musculoskeletal Systems in Small Animals · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row C
Keywords: Diabetes 3.0T magnetic resonance imaging Animal Model Fat fraction (FF)
Accepted
Jujia Li 1, Jian Zhao1, Ying Liu1, Ning Zheng2, Qian Meng1, Shuo Chen1, Xiaojian Zhang1
1Medical Imaging Department, Hebei Medical University Third Hospital, shijiazhuang, China
2Clinical and Technical Support, Philips Healthcare (Beijing), Beijing, China
Presenting Author: Jujia Li

Synopsis

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References

1. Zheng Y, Yang S, Chen X, et al. The Correlation between Type 2 Diabetes and Fat Fraction in Liver and Pancreas: A Study using MR Dixon Technique. Contrast Media Mol Imaging. 2022 Dec 30;2022:7073647. doi: 10.1155/2022/7073647. [doi]
2. Dai F, Zhang Y, Xu D, et al. Effects of long term diabetogenic high fat diet on bone in ovariectomized female rats. Biotech Histochem. 2023 Jan;98(1):20-28. doi: 10.1080/10520295.2022.2083685. [doi]
3. Zhou B, Wu J, Zhao T, et al. Quantification of infrapatellar fat pad fibrosis using magnetic resonance imaging-derived proton density fat fraction: a pathology-controlled study. Quant Imaging Med Surg. 2025 Apr 1;15(4):2694-2706. doi: 10.21037/qims-24-2021. [doi]
4. Athira R, Cannane S, Thushara R, et al. Diagnostic Accuracy of Standalone T2 Dixon Sequence Compared with Conventional MRI in Sacroiliitis. Indian J Radiol Imaging. 2022 Aug 23;32(3):314-323. doi: 10.1055/s-0042-1753467. [doi]
5. Shi GZ, Chen H, Zeng WK, et al. R2* value derived from multi-echo Dixon technique can aid discrimination between benign and malignant focal liver lesions. World J Gastroenterol. 2021 Mar 28;27(12):1182-1193. doi: 10.3748/wjg.v27.i12.1182. [doi]
6. Chiabai O, Van Nieuwenhove S, Vekemans MC, Tombal B, Peeters F, Wuts J, Triqueneaux P, Omoumi P, Kirchgesner T, Michoux N, Lecouvet FE. Whole-body MRI in oncology: can a single anatomic T2 Dixon sequence replace the combination of T1 and STIR sequences to detect skeletal metastasis and myeloma? Eur Radiol. 2023 Jan;33(1):244-257. doi: 10.1007/s00330-022-09007-8. [doi]
7. Craft ML, Edwards M, Jain TP, et al. R2 and R2* MRI assessment of liver iron content in an undifferentiated diagnostic population with hyperferritinaemia, and impact on clinical decision making. Eur J Radiol. 2021 Feb;135:109473. doi: 10.1016/j.ejrad.2020.109473. [doi]

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http://echo.ismrm.org/p/ISMRM2026/462-04-009