Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
569-01-001 ISMRM Abstract

Improved Visualization of Neuromelanin using Frequency Swept Magnetization Transfer Prepared TFL Sequence at 7T MRI

Primary: Acquisition & Reconstruction - New Signal Preparation Schemes
Secondary: Neuro - Parkinson's Disease
569-01-001 · Signal Modeling and Signal Preparation: Novel Approaches · Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row J
Keywords: Magnetization transfer 7T Neuromelanin-Sensitive MRI
Accepted
QING LI1, Ying-Hua Chu1, Yuyang Zhang2, Jianxun Qu 3
1MR Research Collaboration, Siemens Healthineers Ltd., Shanghai, China
2The First Affiliated Hospital of Fujian Medical University, Fuzhou, China
3MR Research Collaboration, Siemens Healthineers, Beijing China, China
Presenting Author: Jianxun Qu

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. 1. Filimontseva A, Fu Y, Vila M, Halliday GM. Neuromelanin and selective neuronal vulnerability to parkinson’s disease. Trends Neurosci. 2025;48(6):445-459. doi:10.1016/j.tins.2025.04.005 [doi]
2. 2. Wengler K, Trujillo P, Cassidy CM, Horga G. Neuromelanin-sensitive MRI for mechanistic research and biomarker development in psychiatry. Neuropsychopharmacology. 2025;50(1):137-152. doi:10.1038/s41386-024-01934-y [doi]
3. 3. Priovoulos N, Jacobs HIL, Ivanov D, Uludağ K, Verhey FRJ, Poser BA. High-resolution in vivo imaging of human locus coeruleus by magnetization transfer MRI at 3T and 7T. NeuroImage. 2018;168:427-436. doi:10.1016/j.neuroimage.2017.07.045 [doi]
4. 4. Doppler CEJ, Kinnerup MB, Brune C, et al. Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in parkinson’s disease. Brain. 2021;144(9):2732-2744. doi:10.1093/brain/awab236 [doi]
5. 5. Ehrminger M, Latimier A, Pyatigorskaya N, et al. The coeruleus/subcoeruleus complex in idiopathic rapid eye movement sleep behaviour disorder. Brain. 2016;139(4):1180-1188. doi:10.1093/brain/aww006 [doi]
6. 6. Oshima S, Fushimi Y, Okada T, et al. Neuromelanin-sensitive magnetic resonance imaging using DANTE pulse. Mov Disord Off J Mov Disord Soc. 2021;36(4):874-882. doi:10.1002/mds.28417 [doi]
7. 7. Andikoetxea BG, Martín‐Bastida A, Vidorreta M, et al. Neuromelanin contrast optimization and improved visualization of the substantia nigra in a 3D gradient‐echo sequence with magnetization transfer. NMR Biomed. 2025;38(9):e70123. doi:10.1002/nbm.70123 [doi]
8. 8. Alsop DC, Ercan E, Girard OM, et al. Inhomogeneous magnetization transfer imaging: Concepts and directions for further development. NMR Biomed. 2023;36(6):e4808. doi:10.1002/nbm.4808 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/569-01-001