Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
369-02-011 ISMRM Abstract

Choroid Plexus Hemodynamic Impairment and Glymphatic Dysfunction in Parkinson's Disease Revealed by Multi-Delay ASL

Primary: Neuro
Secondary: Brain Function and fMRI
369-02-011 · Imaging Parkinson’s Disease: Multimodal Biomarkers of Progression and Phenotype · Monday, 11 May, 9:15 AM–10:10 AM · Digital Posters Row J
Accepted
Song'an Shang 1, Jing Zhang2, Jing Ye1,3
1Northern Jiangsu People’s Hospital, Yangzhou, China
2MR Research Collaboration Team, Shanghai, China
3Department of Radiology, Northern Jiangsu People’s Hospital, Yangzhou, China
Presenting Author: Song'an Shang

Synopsis

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References

1. Simuni T, Chahine LM, Poston K, et al. A biological definition of neuronal alpha-synuclein disease: Towards an integrated staging system for research [J]. Lancet Neurol, 2024;23(2):178-190. https://doi.org/10.1016/S1474-4422(23)00405-2 [doi]
2. Calabresi P, Mechelli A, Natale G, et al. Alpha-synuclein in parkinson's disease and other synucleinopathies: From overt neurodegeneration back to early synaptic dysfunction [J]. Cell Death Dis, 2023;14(3):176. https://doi.org/10.1038/s41419-023-05672-9 [doi]
3. Zhang Y, Zhang C, He XZ, et al. Interaction between the glymphatic system and alpha-synuclein in parkinson's disease [J]. Mol Neurobiol, 2023;60(4):2209-2222. https://doi.org/10.1007/s12035-023-03212-2 [doi]
4. Yue Y, Zhang X, Lv W, et al. Interplay between the glymphatic system and neurotoxic proteins in parkinson's disease and related disorders: Current knowledge and future directions [J]. Neural Regen Res, 2024;19(9):1973-1980. https://doi.org/10.4103/1673-5374.390970 [doi]
5. Shen T, Yue Y, Ba F, et al. Diffusion along perivascular spaces as marker for impairment of glymphatic system in parkinson's disease [J]. NPJ Parkinsons Dis, 2022;8(1):174. https://doi.org/10.1038/s41531-022-00437-1 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/369-02-011