563-02-003 ISMRM Abstract

In vivo MR elastography reveals cartilage stiffness changes linked to altered gait patterns post-ACL surgery

Primary: Musculoskeletal - Cartilage

Secondary: Acquisition & Reconstruction - Quantitative Imaging: spine, MSK, others

563-02-003 · Cartilage 2026 · Wednesday, 13 May, 9:15 AM–10:10 AM · Digital Posters Row D

Keywords: Elastography Osteoarthritis Strain ACL Reconstruction Stiffness Imaging

Accepted

Emily Y Miller, Timothy W Lowe, Hongtian Zhu, Stéphane Avril, Corey Neu ¹

¹University of Colorado Boulder, Boulder, United States of America

Presenting Author: Corey Neu

Synopsis

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References

1. Thomas AC, Hubbard-Turner T, Wikstrom EA, Palmieri-Smith RM. Epidemiology of Posttraumatic Osteoarthritis. J Athl Train. 2017;52(6):491. doi:10.4085/1062-6050-51.5.08 [doi]

2. Eckstein F, Wirth W, Hunter DJ, et al. Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis - data from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage. 2010;18(6):760-768. doi:10.1016/j.joca.2009.12.009 [doi]

3. Zhu H, Miller EY, Lee W, Wilson RL, Neu CP. In vivo human knee varus-valgus loading apparatus for analysis of MRI-based intratissue strain and relaxometry. J Biomech. 2024;171:112171. doi:10.1016/J.JBIOMECH.2024.112171 [doi]

4. Lee W, Miller EY, Zhu H, Luetkemeyer CM, Schneider SE, Neu CP. High frame rate deformation analysis of knee cartilage by spiral dualMRI and relaxation mapping. Magn Reson Med. 2023;89(2):694-709. doi:10.1002/MRM.29487 [doi]

5. Lee W, Miller EY, Zhu H, Schneider SE, Reiter DA, Neu CP. Multi-frame biomechanical and relaxometry analysis during in vivo loading of the human knee by spiral dualMRI and compressed sensing. Magn Reson Med. 2023;90(3):995-1009. doi:10.1002/MRM.29690 [doi]

6. Mei Y, Deng J, Guo X, Goenezen S, Avril S. Introducing regularization into the virtual fields method (VFM) to identify nonhomogeneous elastic property distributions. Comput Mech. 2021;67(6):1581-1599. doi:10.1007/S00466-021-02007-3/FIGURES/21 [doi]

7. Miller CE, Jordan JH, Thomas A, Weis JA. Developing a biomechanical model-based elasticity imaging method for assessing hormone receptor positive breast cancer treatment-related myocardial stiffness changes. Journal of Medical Imaging. 2021;8(5):56002-56003. doi:10.1117/1.JMI.8.5.056002 [doi]

8. Miller CE, Jordan JH, Douglas E, Ansley K, Thomas A, Weis JA. Reproducibility assessment of a biomechanical model-based elasticity imaging method for identifying changes in left ventricular mechanical stiffness. https://doi.org/101117/1JMI95056001. 2022;9(5):056001. doi:10.1117/1.JMI.9.5.056001 [doi]

9. Linus A, Tanska P, Nippolainen E, et al. Site-specific elastic and viscoelastic biomechanical properties of healthy and osteoarthritic human knee joint articular cartilage. J Biomech. 2024;169. doi:10.1016/J.JBIOMECH.2024.112135 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/563-02-003