Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
364-01-009 ISMRM Abstract

Mapping Cerebrovascular Reactivity and Vascular Delay across Glioma Subregions Using Multi-Echo BOLD fMRI with Breath-holding

Primary: Neuro - Tumors
Secondary: Brain Function and fMRI - fMRI Analysis
364-01-009 · fMRI: Analyses · Monday, 11 May, 8:20 AM–9:15 AM · Digital Posters Row E
Keywords: Glioma Cerebrovascular reactivity Breath-hold Multi-echo fMRI Neurovascular uncoupling
Accepted
Cristina E Comella Luengo1, Lia M Hocke1, Stefano Moia2, Santiago Gil Robles3,4, Iñigo Pomposo3, Manuel Carreiras1,5,6, Ileana Quiñones6,7, César Caballero-Gaudes 1,6
1Basque Center on Cognition, Brain and Language, San Sebastian - Donostia, Spain
2Department of Cognitive Neuroscience, FPN, Maastricht University, Netherlands
3BioBizkaia Research Institute, Bilbao, Spain
4Hospital Quiron, Madrid, Spain
5Universidad de País Vasco, San Sebastián, Spain
6Ikerbasque, Basque Foundation for Science, Bilbao, Spain
7BioGipuzkoa Health Research Institute, San Sebastian, Spain
Presenting Author: César Caballero-Gaudes

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. J.J. Pillai, D.J. Mikulis Cerebrovascular Reactivity Mapping: An Evolving Standard for Clinical Functional Imaging American Journal of Neuroradiology Jan 2015, 36 (1) 7-13; DOI: 10.3174/ajnr.A3941 [doi]
2. Iranmahboob, et al. (2016), Vascular Reactivity Maps in Patients with Gliomas Using Breath-Holding BOLD fMRI. J Neuroimaging, 26: 232-239. https://doi.org/10.1111/jon.12278 [doi]
3. Fierstra J, et al. Diffuse gliomas exhibit whole brain impaired cerebrovascular reactivity. Magn Reson Imaging. 2018 Jan;45:78-83. doi: 10.1016/j.mri.2017.09.017. Epub 2017 Oct 3. PMID: 28986176. [doi] [pmid]
4. Giovanni Muscas et al. Hemodynamic investigation of peritumoral impaired blood oxygenation-level dependent cerebrovascular reactivity in patients with diffuse glioma, Magnetic Resonance Imaging, Volume 70, 2020, Pages 50-56, ISSN 0730-725X, https://doi.org/10.1016/j.mri.2020.03.012 [doi]
5. Stefano Moia et al., ICA-based denoising strategies in breath-hold induced cerebrovascular reactivity mapping with multi echo BOLD fMRI, NeuroImage, Volume 233, 2021, 117914, ISSN 1053-8119, https://doi.org/10.1016/j.neuroimage.2021.117914. [doi]
6. Bright, M. G. & Murphy, K. (2013). Neuroimage, 83, 559-568. https://doi.org/10.1016/j.neuroimage.2013.07.007 [doi]
7. Markello, R & DuPre, E. (2018). Peakdet [Computer software]. https://doi.org/10.5281/zenodo.7244954 [doi]
8. DuPre et al., (2021). TE-dependent analysis of multi-echo fMRI with tedana. Journal of Open Source Software, 6(66), 3669, https://doi.org/10.21105/joss.03669 [doi]
9. Uruñuela, E. (2021). Rica (Version v1.0.17) [Computer software]. https://doi.org/10.5281/zenodo.5788350 [doi]
10. Moia, S (2023). Phys2cvr (Version v.0.18.0) [Computer software]. https://doi.org/10.5281/zenodo.6461353 [doi]
11. James K Ruffle et al. Brain tumour segmentation with incomplete imaging data, Brain Communications, Volume 5, Issue 2, 2023, fcad118, https://doi.org/10.1093/braincomms/fcad118 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/364-01-009