666-01-015 ISMRM Abstract

Kinetic-Anchored IDEAL CSI for HP 13C Pyruvate: Center-k Estimation and Voxel-wise Metabolite Imaging

Primary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging

Secondary: Contrast Mechanisms - Hyperpolarized MR (Non-Gas)

666-01-015 · Hyperpolarization: Novel Methods · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row G

Keywords: Kinetic Modeling Hyperpolarized 13C Chemical Shift-Encoded MRI

Accepted

Ching-Yi Hsieh ^1,2, Ying-Chieh Lai^2,3, Kuan-Ying Lu², Gigin Lin^1,2

¹Research Center for Radiation Medicine, Chang Gung University, Taoyuan, Taiwan

²Clinical Metabolomics Core Lab, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan

³Department of Medical Imaging and Radiological Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

Presenting Author: Ching-Yi Hsieh

Synopsis

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References

1. Nelson, S.J., J. Kurhanewicz, D.B. Vigneron, et. al., Metabolic imaging of patients with prostate cancer using hyperpolarized [1-(13)C]pyruvate. Sci Transl Med, 2013. 5(198): p. 198ra108.

2. Wiesinger, F., E. Weidl, M.I. Menzel, et. al., IDEAL spiral CSI for dynamic metabolic MR imaging of hyperpolarized [1- 13C]pyruvate. Magnetic Resonance in Medicine, 2012. 68(1): p. 8-16.

3. Beatty PJ, Nishimura DG, Pauly JM. Rapid gridding reconstruction with a minimal oversampling ratio. IEEE Trans Med Imaging. 2005 Jun;24(6):799-808. doi: 10.1109/TMI.2005.848376. PMID: 15959939. [doi] [pmid]

4. Lai, Y.C., C.Y. Hsieh, K.Y. Lu, et. al., Monitoring Early Glycolytic Flux Alterations Following Radiotherapy in Cancer and Immune Cells: Hyperpolarized Carbon-13 Magnetic Resonance Imaging Study. Metabolites, 2021. 11(8).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/666-01-015