Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
568-03-009 ISMRM Abstract

Relaxivities and Liver Enhancement of Gadopiclenol versus Gadobenate: A Randomized Cross-Over Study

Primary: Contrast Mechanisms - Contrast Agents
Secondary: Contrast Mechanisms - Relaxometry
568-03-009 · MR Biomarkers of Hepatic Steatosis, Fibrosis, and Liver Disease · Wednesday, 13 May, 1:40 PM–2:35 PM · Digital Posters Row I
Keywords: Contrast Mechanisms Dynamic Contrast-Enhanced MRI T1-Weighted Contrast-Enhanced MRI Gadopiclenol Relaxivity
Accepted
Julius F Heidenreich 1,2, Daiki Tamada2, James Rice2, Felix Schön2,3, Garrett C Fullerton2, Ali Pirasteh2, Scott B Reeder2,4,5,6,7,8
1Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany
2Department of Radiology, University of Wisconsin - Madison, Madison, United States of America
3Institute and Polyclinic for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Carl Gustav Carus Dresden, TU Dresden, Dresden, Germany
4University of Wisconsin - Madison, Madison, United States of America
5Department of Biomedical Engineering, University of Wisconsin - Madison, Madison, United States of America
6Department of Medicine, University of Wisconsin - Madison, Madison, United States of America
7Department of Emergency Medicine, University of Wisconsin - Madison, Madison, United States of America
8Department of Medical Physics, University of Wisconsin - Madison, Madison, United States of America
Presenting Author: Julius F Heidenreich

Synopsis

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References

1. Kuhl C, Csőszi T, Piskorski W, et al. Efficacy and Safety of Half-Dose Gadopiclenol versus Full-Dose Gadobutrol for Contrast-enhanced Body MRI. Radiology. 2023;308(1). doi:10.1148/radiol.222612 [doi]
2. Robic C, Port M, Rousseaux O, et al. Physicochemical and Pharmacokinetic Profiles of Gadopiclenol: A New Macrocyclic Gadolinium Chelate With High T1 Relaxivity. Invest Radiol. 2019;54(8):475-484. doi:10.1097/RLI.0000000000000563 [doi]
3. Maki J, Clark T, Barker A, et al. R1, R2 and R2* Relaxivity Measurements of the Contrast Agent Gadopiclenol in Human Blood; Application to Administration Strategies. In: Proc. Intl. Soc. Mag. Reson. Med. 33. ; 2025:0778. doi:10.58530/2025/0778 [doi]
4. van der Heijden RA, Tamada D, Mao L, et al. Relaxivity and In Vivo Human Performance of Brand Name Versus Generic Ferumoxytol. Invest Radiol. 2025;60(5):319-327. doi:10.1097/RLI.0000000000001130 [doi]
5. Fullerton G, Tamada D, Muslu Y, et al. Saturation Recovery Chemical Shift-Encoded T1 Mapping in the Liver. In: Proc. Intl. Soc. Mag. Reson. Med. 33. ; 2025:0816. doi:10.58530/2025/0816 [doi]
6. Pittas NN, Pavlides M, Mózes FE. Investigation of the Effect of Isotonic Drinks on Quantitative MRI Markers of the Liver and Spleen. NMR Biomed. 2025;38(11). doi:10.1002/nbm.70156 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/568-03-009