Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
305-04-005 ISMRM Abstract

Robust muscle function analysis from time-resolved 4D strain measurements

Accepted
Max H.C. van Riel 1, David G.J. Heesterbeek1, Ray Sheombarsing1, Martijn Froeling2, Tristan van Leeuwen3,4, Cornelis A van den Berg1, Alessandro A Sbrizzi1
1Computational Imaging Group for MRI Therapy & Diagnostics, Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
2Precision Imaging Group, Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands
3Mathematical Institute, Utrecht University, Utrecht, Netherlands
4Computational Imaging Group, Centrum Wiskunde & Informatica, Amsterdam, Netherlands
Presenting Author: Max H.C. van Riel

Synopsis

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References

1. Sinha U, Malis V, Csapo R, Moghadasi A, Kinugasa R, Sinha S. Age-related differences in strain rate tensor of the medial gastrocnemius muscle during passive plantarflexion and active isometric contraction using velocity encoded MR imaging: Potential index of lateral force transmission. Magn Reson Med. 2015;73(5):1852-1863. doi:10.1002/mrm.25312 [doi]
2. Mazzoli V, Gottwald LM, Peper ES, et al. Accelerated 4D phase contrast MRI in skeletal muscle contraction. Magn Reson Med. 2018;80(5):1799-1811. doi:10.1002/mrm.27158 [doi]
3. Hooijmans MT, Schlaffke L, Bolsterlee B, Schlaeger S, Marty B, Mazzoli V. Compositional and Functional MRI of Skeletal Muscle: A Review. J Magn Reson Imaging. 2024;60(3):860-877. doi:10.1002/jmri.29091 [doi]
4. van Riel MHC, van Leeuwen T, van den Berg CAT, Sbrizzi A. Time-Resolved Reconstruction of Motion, Force, and Stiffness Using Spectro-Dynamic MRI. IEEE Trans Comput Imaging. 2023;9:917-927. doi:10.1109/TCI.2023.3324757 [doi]
5. van Riel MHC, Heesterbeek DGJ, Sheombarsing RSS, et al. 4D Time-Resolved Strain Tensor Analysis Using Spectro-Dynamic MRI Reveals Muscle Activation Patterns. In: Proc. Intl. Soc. Mag. Reson. Med. Vol 33. 2025. doi:10.58530/2025/0982 [doi]
6. Froeling M. QMRTools: a Mathematica toolbox for quantitative MRI analysis. J Open Source Softw. 2019;4(38):1204. doi:10.21105/joss.01204 [doi]
7. Prieto C, Doneva M, Usman M, et al. Highly efficient respiratory motion compensated free-breathing coronary mra using golden-step Cartesian acquisition. J Magn Reson Imaging. 2015;41(3):738-746. doi:10.1002/jmri.24602 [doi]
8. Klein S, Staring M, Murphy K, Viergever MA, Pluim JPW. elastix: A Toolbox for Intensity-Based Medical Image Registration. IEEE Trans Med Imaging. 2010;29(1):196-205. doi:10.1109/TMI.2009.2035616 [doi]
9. Heesterbeek DGJ, van Riel MHC, Sheombarsing RSS, et al. Quasi-static in vivo elastography from internal displacement information only. arXiv. Preprint posted online October 14, 2025. doi:10.48550/arXiv.2510.12609 [doi]

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