Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
468-01-012 ISMRM Abstract

Normative references for amygdala subregions across the lifespan and heterogeneous alterations in neurological diseases.

Primary: Neuro - Aging
Secondary: Neuro - Other Neurodegeneration
468-01-012 · Quantitative Neuroimaging of Neurodegeneration, Metabolism, and Brain Microstructure · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row I
Keywords: Neurodegeneration Neurodevelopment Brain chart Amygdala
Accepted
Chao Zhang 1, Zhizheng Zhuo1, Renlong Zhang2, Shan Lv1, Yifei Zhang3, Yaou Liu1
1Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2Neusoft Medical Systems Co., Ltd., Hangzhou, China
3GE HealthCare MR Research, Beijing, China
Presenting Author: Chao Zhang

Synopsis

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References

1. Auer H, Cabalo DG, Rodríguez-Cruces R, et al. From histology to macroscale function in the human amygdala. eLife 2025;13 doi: 10.7554/eLife.101950 [doi]
2. Bethlehem RAI, Seidlitz J, White SR, et al. Brain charts for the human lifespan. Nature 2022;604(7906):525-33. doi: 10.1038/s41586-022-04554-y [doi]
3. Appleton J, Finn Q, Zanotti-Fregonara P, et al. Brain inflammation co-localizes highly with tau in mild cognitive impairment due to early-onset Alzheimer's disease. Brain 2025;148(1):119-32. doi: 10.1093/brain/awae234 [doi]
4. Chen L, Nagaraja C, Daniels S, et al. Synaptic location is a determinant of the detrimental effects of α-synuclein pathology to glutamatergic transmission in the basolateral amygdala. Elife 2022;11 doi: 10.7554/eLife.78055 [doi]
5. Cortese R, Battaglini M, Prados F, et al. Grey Matter Atrophy and its Relationship with White Matter Lesions in Patients with Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder, and Multiple Sclerosis. Ann Neurol 2024;96(2):276-88. doi: 10.1002/ana.26951 [doi]
6. Cheng Z, Nie W, Leng J, et al. Amygdala and cognitive impairment in cerebral small vessel disease: structural, functional, and metabolic changes. Frontiers in Neurology 2024;15 doi: 10.3389/fneur.2024.1398009 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/468-01-012