Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
465-05-011 ISMRM Abstract

Deep Learning-Enhanced Diffusion MRI Improves Connectome-guided Targeting for SCC DBS in Depression

Primary: Neuro - Neuromodulation
Secondary: Interventional - MR-Guided Neuromodulation
465-05-011 · Tractography Applications · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row F
Keywords: Deep Brain Stimulation Deep learning reconstruction Depression Subvoxel quantitative susceptibility mapping Connectome-based targeting
Accepted
Ha Neul Song1, Jaemin Shin 2,3, Brian H Kopell1,4,5, Suchandrima Banerjee6, Helen S Mayberg7, Ki Sueng Choi8
1Nash Family Center for Advanced Circuit Therapeutics, Icahn School of Medicine at Mount Sinai, New York, United States of America
2GE HealthCare, San Ramon, United States of America
3GE HealthCare., NY, United States of America
4Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, United States of America
5Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, United States of America
6GE HealthCare Global MR Applications & Workflow, Menlo Park, United States of America
7Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States of America
8Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, United States of America
Presenting Author: Jaemin Shin

Synopsis

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References

1. Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C, Schwalb JM, Kennedy SH. Deep brain stimulation for treatment-resistant depression. Neuron. 2005 Mar 3;45(5):651-60.
2. Choi KS, Mayberg H. Connectomic DBS in major depression. InConnectomic Deep Brain Stimulation 2022 Jan 1 (pp. 433-447). Academic Press.
3. Riva-Posse P, Choi KS, Holtzheimer PE, Crowell AL, Garlow SJ, Rajendra JK, McIntyre CC, Gross RE, Mayberg HS. A connectomic approach for subcallosal cingulate deep brain stimulation surgery: prospective targeting in treatment-resistant depression. Molecular psychiatry. 2018 Apr;23(4):843-9.
4. Maier-Hein KH, Neher PF, Houde JC, Côté MA, Garyfallidis E, Zhong J, Chamberland M, Yeh FC, Lin YC, Ji Q, Reddick WE. The challenge of mapping the human connectome based on diffusion tractography. Nature communications. 2017 Nov 7;8(1):1349.
5. Lebel RM. Performance characterization of a novel deep learning-based MR image reconstruction pipeline. arXiv preprint arXiv:2008.06559. 2020 Aug 14.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/465-05-011