Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
464-03-002 ISMRM Abstract

Compensatory Reorganization of Superior Parietal Lobule Networks in ALS: A Longitudinal Resting-State fMRI Study

Accepted
Sadegh Ghaderi 1,2,3, Sana Mohammadi2,4,5, Sanjay Kalra6, Seyed Amir Hossein Batouli7
1Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of)
2Neuromuscular Research Center, Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of)
3Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada
4Department of Medical Sciences, School of Medicine, Iran University of Medical Sciences, Tehran, Iran (Islamic Republic of)
5School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran (Islamic Republic of)
6Neuroscience and Mental Health Institute, Division of Neurology, Department of Medicine, and Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada, Canada
7Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran, Iran (Islamic Republic of)
Presenting Author: Sadegh Ghaderi

Synopsis

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References

1. Zago S, Lorusso L, Aiello EN, et al. (2022). Cognitive and behavioral involvement in ALS has been known for more than a century. Neurol Sci, 43(12):6741-6760. doi:10.1007/s10072-022-06340-0 [doi]
2. Wang J, Yang Y, Fan L, et al. (2014). Convergent functional architecture of the superior parietal lobule unraveled with multimodal neuroimaging approaches. Human Brain Mapping, 36(1):238. doi:10.1002/hbm.22626 [doi]
3. Zhou F, Gong H, Li F, et al. (2013). Altered motor network functional connectivity in amyotrophic lateral sclerosis: a resting-state functional magnetic resonance imaging study. Neuroreport, 24(12):657-662. doi:10.1097/WNR.0b013e328363148c [doi]
4. Costa J, Swash M, de Carvalho M. (2012). Awaji Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis: A Systematic Review. Archives of Neurology, 69(11):1410-1416. doi:10.1001/archneurol.2012.254 [doi]
5. Whitfield-Gabrieli S, Nieto-Castanon A. (2012). Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks. Brain Connect, 2(3):125-141. doi:10.1089/brain.2012.0073 [doi]
6. Friston KJ, Penny WD, Ashburner J, Kiebel SJ, Nichols TE. (2006). Statistical Parametric Mapping: The Analysis of Functional Brain Images. Academic Press.
7. Kalra S, Cashman NR, Caramanos Z, Genge A, Arnold DL. (2003). Gabapentin Therapy for Amyotrophic Lateral Sclerosis: Lack of Improvement in Neuronal Integrity Shown by MR Spectroscopy. AJNR Am J Neuroradiol, 24(3):476-480.
8. Menon V, Uddin LQ. (2010). Saliency, switching, attention and control: a network model of insula function. Brain Struct Funct, 214(5-6):655-667. doi:10.1007/s00429-010-0262-0 [doi]

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