466-03-005 Registered Abstract

Visualization of Glymphatic Flow Using IR-Prepared GRE Diffusion and Directional ΔS Mapping

Primary: Neuro - Neurofluids

Secondary: Acquisition & Reconstruction - New Signal Preparation Schemes

466-03-005 · Pulse Sequences with a Focus on Quantitative Imaging · Tuesday, 12 May, 1:40 PM–2:35 PM · Digital Posters Row G

Keywords: Neurofluids Cerebrospinal fluid Diffusion-weighted MRI Glymphatic system function

Accepted

Se-Hong Oh^1,2, Ken Sakaie^2,3, Gawon Lee¹, Stephen E Jones^2,4, Mark Lowe ^2,3,4,5

¹Department of Biomedical Engineering, Hankuk university of Foreign Studies, gyeonggi-do, Korea, Republic of

²Diagnostic Radiology, Cleveland Clinic, Cleveland, United States of America

³Cleveland Clinic, Cleveland, United States of America

⁴Imaging Institute, Cleveland Clinic, Cleveland, United States of America

⁵Department of Diagnostic Radiology, Imaging Institute, Cleveland Clinic, Cleveland, United States of America

Presenting Author: Mark Lowe

Synopsis

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References

1. Buccellato FR, D'Anca M, Serpente M, Arighi A, Galimberti D. The Role of Glymphatic System in Alzheimer's and Parkinson's Disease Pathogenesis. Biomedicines. 2022 Sep 13;10(9):2261. doi: 10.3390/biomedicines10092261. PMID: 36140362; PMCID: PMC9496080. [doi] [pmid]

2. 2. Tomas Bohr, Poul G. Hjorth, Sebastian C. Holst, Sabina Hrabětová, Vesa Kiviniemi, Tuomas Lilius, Iben Lundgaard, Kent-Andre Mardal, Erik A. Martens, Yuki Mori, U. Valentin Nägerl, Charles Nicholson, Allen Tannenbaum, John H. Thomas, Jeffrey Tithof, Helene Benveniste, Jeffrey J. Iliff, Douglas H. Kelley, Maiken Nedergaard, The glymphatic system: Current understanding and modeling, iScience, Volume 25, Issue 9, 2022, 104987

3. Jenkinson M, Beckmann CF, Behrens TE, Woolrich MW, Smith SM. Fsl. Neuroimage. 2012;62(2):782-90. doi: 10.1016/j.neuroimage.2011.09.015. PubMed PMID: 21979382 [doi] [pmid]

4. Andersson JLR, Sotiropoulos SN. An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging. Neuroimage. 2016;125:1063-78. doi: 10.1016/j.neuroimage.2015.10.019. PubMed PMID: 26481672; PMCID: PMC4692656 [doi] [pmid]

5. Tournier JD, Smith R, Raffelt D, Tabbara R, Dhollander T, Pietsch M, Christiaens D, Jeurissen B, Yeh CH, Connelly A. MRtrix3: A fast, flexible and open software framework for medical image processing and visualisation. Neuroimage. 2019;202:116137. doi: 10.1016/j.neuroimage.2019.116137. PubMed PMID: 31473352. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/466-03-005