Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
463-05-013 ISMRM Abstract

MRMI assessment of therapeutic efficacy of P53-R175H targeting nanovaccine to treat pancreatic cancer

Primary: Contrast Mechanisms - Contrast Agents
Secondary: Body - Pancreas
463-05-013 · Malignant Tumor in the Body · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row D
Keywords: Pancreatic cancer Contrast-enhancement Animal MRI Immunotherapy
Accepted
Yanqing Wang1, Yue Jiang1, Hong Wang1, Victoria Laney2, Abhinav Acharya1, Jordan Winter3, Lily Li Wang4, Zheng-Rong Lu 1
1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, United States of America
2Department of Biomedical Engineering, University of Illinois Chicago, Chicago, United States of America
3University Hospitals, Cleveland, United States of America
4Department of translational Hematology and oncology Research, Cleveland Clinic, Cleveland, United States of America
Presenting Author: Zheng-Rong Lu

Synopsis

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References

1. C. Wagner, A. Burger, M. Radsak, S. Blum, F. Hug, G.M. Hansch, Fibronectin synthesis by activated T lymphocytes: up-regulation of a surface-associated isoform with signalling function, Immunology 99(4) (2000) 532-9.PMID: 10792500 [pmid]
2. V.E.A. Laney, W. Zhao, I.M. Hwang, E. Hampson, J. Dong, R.C. Hall, K. Weber-Bonk, X. Yuan, E. Delaney, H. Gilmore, R. Keri, J. Winter, L.L. Wang, Z.R. Lu, MR molecular imaging for monitoring and predicting tumor responses to immunotherapy, Theranostics 15(18) (2025) 10045-10063.PMID: 41041061 [pmid]
3. Y. Wang, D. Sun, V. Laney, H. Wang, L.L. Wang, Z.R. Lu, Challenges and opportunities on achieving an adequate delivery efficiency and immunogenicity with peptide-based anticancer vaccines, Adv Drug Deliv Rev 225 (2025) 115675. PMID:40818568 [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/463-05-013