Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
302-02-002 ISMRM Abstract

Phase-resolved functional lung (PREFUL) versus arterial spin labeling (ASL) MRI for noninvasive measurement of lung perfusion

Primary: Contrast Mechanisms - Arterial Spin Labelling
Secondary: Body - Lung
302-02-002 · Take a Breath: Chest, Thoracic, and Pulmonary MRI · Monday, 11 May, 8:20 AM–10:10 AM · Hall 1B
Keywords: Perfusion Arterial spin labeling Lung MRI PCASL lung perfusion imaging PREFUL MRI
Accepted
Petros Martirosian 1, Andreas Voskrebenzev2,3, Filip Klimeš2,3,4, Rolf Pohmann5, Thomas Küstner6, Martin Schwartz1, Fritz Schick1, Jens Vogel-Claussen2,3,7, Cecilia Liang8
1Section on Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital of Tuebingen, Tuebingen, Germany
2Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany
3Biomedical Research in Endstage and Obstructive Lung Disease, German Center for Lung Research (DZL), Munich, Germany
4Department of Radiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
5Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany
6Medical Image and Data Analysis (MIDAS.lab), Department of Diagnostic and Interventional Radiology, University Hospital of Tuebingen, Tuebingen, Germany
7Department of Radiology, Charité – Universitätsmedizin Berlin, Berlin, Germany
8Department of Diagnostic and Interventional Radiology, University Hospital of Tuebingen, Tuebingen, Germany
Presenting Author: Petros Martirosian

Synopsis

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References

1. Bolar DS, Levin DL, Hopkins SR, et al. Quantification of Regional Pulmonary Blood Flow Using ASL-FAIRER. Magn Reson Med 2006;55:1308–17.
2. Martirosian P, Boss A, Fenchel M, et al. Quantitative lung perfusion mapping at 0.2 T using FAIR True-FISP MRI. Magn Reson Med 2006;55:1065–1074
3. Seith F, Pohmann R, Schwartz M, et al. Imaging Pulmonary Blood Flow Using Pseudocontinuous Arterial Spin Labeling (PCASL) With Balanced Steady-State Free-Precession (bSSFP) Readout at 1.5T. J Magn Reson Imaging. 2020;52:1767-82.
4. Othman AE, Liang C, Komma Y, et al. Free-breathing Arterial Spin Labeling MRI for the Detection of Pulmonary Embolism. Radiology. 2023;307(3):e221998.
5. Voskrebenzev A, Gutberlet M, Klimeš F, et al. Feasibility of quantitative regional ventilation and perfusion mapping with phase-resolved functional lung (PREFUL) MRI in healthy volunteers and COPD, CTEPH, and CF patients. Magn Reson Med 2018;79:2306-14.
6. Glandorf J, Klimeš F, Behrendt L, et al. Perfusion quantification using voxel-wise proton density and median signal decay in PREFUL MRI. Magn Reson Med 2021;86:1482-93.
7. Bauman G, Puderbach M, Deimling M, et al. Non-contrast-enhanced perfusion and ventilation assessment of the human lung by means of fourier decomposition in proton MRI. Magn Reson Med 2009;62:656–64
8. Gilliam C, Küstner T, Blu T. 3D motion flow estimation using local all-pass filters. 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI), 2016; 282–285.
9. Walker SC, Asadi AK, Hopkins SR, et al. A statistical clustering approach to discriminating perfusion from conduit vessel signal contributions in a pulmonary ASL MR image. NMR Biomed 2015;28:1117-24.
10. Forsberg D, Andersson M, Knutsson H. Extending image registration using polynomial expansion to diffeomorphic deformations. In: SSBA symposium on image analysis 2012:4.

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http://echo.ismrm.org/p/ISMRM2026/302-02-002