Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
470-04-100 ISMRM Abstract

Fat Selective Excitation for Fat Signal Cancellation in APT-Weighted Imaging

Primary: Contrast Mechanisms - Fat & Fat/Water Separation
Secondary: Contrast Mechanisms - CEST / APT / NOE
470-04-100 · Fat-Water Separation and Fat Suppression · Tuesday, 12 May, 9:15 AM–10:10 AM · Traditional Posters | Exhibition Hall
Keywords: APT RF Pulse Design RF saturation Fat suppression
Accepted
Holger Eggers 1, Elena Vinogradov2,3, Jochen Keupp1
1Philips Innovative Technologies, Hamburg, Germany
2Department of Radiology, University of Texas Southwestern Medical Center, Dallas, United States of America
3Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, United States of America
Presenting Author: Holger Eggers

Synopsis

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References

1. Zhou J, Lal B, Wilson DA, et al. Amide proton transfer (APT) contrast for imaging of brain tumors. Magn Reson Med 2003; 50:1120-1126.
2. Oh CH, Hilal SK, Cho ZH. Selective partial inversion recovery (SPIR) in steady state for selective saturation magnetic resonance imaging (MRI). Proc SMRM 1988; 1042.
3. Keupp J, Dimitrov IE, Eggers H, et al. Z-spectral fitting for fat correction of APT/CEST MRI including fat suppression pulses to improve body applications. Proc ISMRM 2023; 2989.
4. Eggers H, Keupp J. Variable flip angle SPIR for fat suppression in APT-weighted imaging. Proc ISMRM 2025; 3518.
5. Hamilton G, Yokoo T, Bydder M, et al. In vivo characterization of the liver fat 1H MR spectrum. NMR Biomed 2011; 24:784-790.
6. Togao O, Keupp J, Hiwatashi A, et al. Amide proton transfer imaging of brain tumors using a self-corrected 3D fast spin-echo Dixon method: Comparison with separate B0 correction. Magn Reson Med 2017; 77:2272-2279.
7. de Graaf RA, Nicolay K. Adiabatic water suppression using frequency selective excitation. Magn Reson Med 1998; 40:690-696.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/470-04-100