666-01-004 ISMRM Abstract

Enhancing in vivo SNR of hyperpolarized pH imaging through T1 prolongation by deuteration of 13C-labelled (Z)-OMPD

Primary: Contrast Mechanisms - Hyperpolarized MR (Non-Gas)

Secondary: Contrast Mechanisms - Molecular Imaging

666-01-004 · Hyperpolarization: Novel Methods · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row G

Keywords: Kidney Hyperpolarized 13C MRI PH imaging (Z)-OMPD T1 relaxation

Accepted

Florian M Gaksch ¹, Alexander Huber^1,2, Jakob Gaubatz¹, Sandra Sühnel¹, Kristin Koetz¹, Nadine Setzer¹, Silvester J Bartsch¹, Martin Grashei¹, Franz Schilling^1,2,3

¹Department of Nuclear Medicine, TUM School of Medicine and Health, TUM University Hospital, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

²German Cancer Consortium (DKTK) partner site Munich, a partnership between DKFZ and TUM University Hospital, Germany

³Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany

Presenting Author: Florian M Gaksch

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References

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8. Grashei M, Wodtke P, Skinner JG, et al. Simultaneous magnetic resonance imaging of pH, perfusion and renal filtration using hyperpolarized 13C-labelled Z-OMPD. Nat Commun. 2023;14:5060. doi: 10.1038/s41467-023-40747-3 [doi]

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http://echo.ismrm.org/p/ISMRM2026/666-01-004