Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
668-02-012 ISMRM Abstract

Sleep-related changes in 1H MRS-visible macromolecules

Primary: Neuro - Neurofluids
Secondary: Neuro - Head & Neck/ENT
668-02-012 · Spectroscopy and Spectroscopic Imaging: Applications · Thursday, 14 May, 9:25 AM–10:20 AM · Digital Posters Row I
Keywords: MRS Sleep Glymphatic clearance Macromolecules
Accepted
Carina Volk1,2, Valeria Jaramillo2,3, Reto Huber2, Ruth O'Gorman Tuura 1,4
1Center for MR Research, University Children's Hospital Zurich, Zurich, Switzerland
2Child Development Center, University Children's Hospital Zurich, Zurich, Switzerland
3University of Surrey, Surrey, United Kingdom
4Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland
Presenting Author: Ruth O'Gorman Tuura

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Cudalbu C, et al. Contribution of macromolecules to brain 1H MR spectra: Experts' consensus recommendations. https://doi.org/10.1002/nbm.4393 [doi]
2. Genovese G, et al. Age-related differences in macromolecular resonances observed in ultra-short-TE STEAM MR spectra at 7 T. doi: 10.1002/mrm.30061 [doi]
3. Marjanska M, et al. Altered macromolecular pattern and content in the aging human brain. doi: 10.1002/nbm.3865 [doi]
4. Akiyama Y, et al. Accumulation of Macromolecules in Idiopathic Normal Pressure Hydrocephalus. doi: 10.2176/nmc.oa.2020-0274 [doi]
5. Xie L, et al. Sleep drives metabolite clearance from the adult brain. doi: 10.1126/science.1241224. [doi]
6. Fultz NE, et al. Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep. doi: 10.1126/science.aax5440. [doi]
7. Aalling NN et al. Cerebral metabolic changes during sleep. doi: 10.1007/s11910-018-0868-9 [doi]
8. Volk C, et al. Diurnal changes in glutamate + glutamine levels of healthy young adults assessed by proton magnetic resonance spectroscopy. doi: 10.1002/hbm.24225 [doi]
9. Iber C, et al. The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications (2007).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/668-02-012