Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
668-01-009 ISMRM Abstract

Ultra high field Deuterium Metabolic Imaging of the human brain using Low-rank Subspace reconstruction

Primary: Contrast Mechanisms - Deuterium
Secondary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging
668-01-009 · Molecular Imaging and Ultra High Field Acquisition · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row I
Keywords: Deuterium Deuterium Metabolic Imaging Low rank Subspace Modelling Deuterium MRSI
Accepted
Konstantinos Olympios 1, Alex A Bhogal2, Narjes Ahmadian1, Jaco J Zwanenburg2, Evita C Wiegers1, KYUNG MIN NAM1
1Precision Imaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands
2Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands
Presenting Author: Konstantinos Olympios

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References

1. De Feyter HM, Behar KL, Corbin ZA, Fulbright RK, Brown PB, McIntyre S, et al. Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo. Sci Adv. 2018;4(8):eaat7314. doi:10.1126/sciadv.aat7314. [doi]
2. de Graaf RA, Hendriks AD, Klomp DWJ, Kumaragamage C, Welting D, Arteaga de Castro CS, Brown PB, McIntyre S, Nixon TW, Prompers JJ, De Feyter HM. On the magnetic field dependence of deuterium metabolic imaging. NMR Biomed. 2020 Mar;33(3):e4235. doi: 10.1002/nbm.4235. Epub 2019 Dec 26. PMID: 31879985; PMCID: PMC7141779. [doi] [pmid]
3. Ahmadian N, Konig MM, Otto S, Tesselaar K, van Eijsden P, Gosselink M, Gursan A, Klomp DW, Prompers JJ, Wiegers EC. Human Brain Deuterium Metabolic Imaging at 7 T: Impact of Different [6,6'-2H2]Glucose Doses. J Magn Reson Imaging. 2025 Mar;61(3):1170-1178. doi: 10.1002/jmri.29532. Epub 2024 Jul 26. PMID: 39058248; PMCID: PMC11803682. [doi] [pmid]
4. Lam F, Liang ZP. A subspace approach to high-resolution spectroscopic imaging. Magn Reson Med. 2014;71(4):1349-1357. doi:10.1002/mrm.25168. [doi]
5. Nam KM, Gursan A, Lee NG, Klomp DWJ, Wijnen JP, Prompers JJ, et al. 3D deuterium metabolic imaging (DMI) of the human liver at 7 T using low-rank and subspace model-based reconstruction. Magn Reson Med. 2024;93(5):1860-1873. doi:10.1002/mrm.30395. [doi]
6. Lam F, Li Y, Guo R, Zhao Y, Clifford B, Liang ZP. Ultrafast magnetic resonance spectroscopic imaging using SPICE with learned subspaces. Magn Reson Med. 2020;83(2):377-390. doi:10.1002/mrm.27980. [doi]
7. Uecker M, Ong F, Tamir JI, Bahri D, Virtue P, Cheng JY, et al. Berkeley Advanced Reconstruction Toolbox (BART). Proc Intl Soc Magn Reson Med. 2015;23:2486. doi:10.5281/zenodo.31907. [doi]
8. Lustig M, Donoho DL, Pauly JM. Sparse MRI: The application of compressed sensing for rapid MR imaging. Magn Reson Med. 2007;58(6):1182-1195. doi:10.1002/mrm.21391. [doi]
9. Vanhamme L, van den Boogaart A, Van Huffel S. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson. 1997;129(1):35-43. doi:10.1006/jmre.1997.1244. [doi]
10. Purvis LAB, Clarke WT, Biasiolli L, Valkovič L, Robson MD, Rodgers CT. OXSA: An open-source magnetic resonance spectroscopy analysis toolbox in MATLAB. PLoS One. 2017;12(9):e0185356. doi:10.1371/journal.pone.0185356. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/668-01-009