660-03-008 ISMRM Abstract

Acid-Responsive Fe₃O₄@MnO₂@CMCS Nanoprobes Enable Dual-Parametric and CEST MRI for Tumor Microenvironment Imaging

Primary: Contrast Mechanisms - Contrast Agents

Secondary: Contrast Mechanisms - CEST / APT / NOE

660-03-008 · Advances in Chemical Exchange MRI: CEST, APT, and NOE I · Thursday, 14 May, 1:40 PM–2:35 PM · Digital Posters Row A

Keywords: Molecular Imaging Chemical exchange saturation transfer Tumor microenvironment Iron quantification

Accepted

Fei-Xiang Hu¹, Pu-Yeh Wu ², Wei-Jun Peng¹, Tong Tong¹

¹Fudan University Shanghai Cancer Center, Shanghai, China

²GE Healthcare, Beijing, China

Presenting Author: Pu-Yeh Wu

Synopsis

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References

1. Yin C et al., The Current Status and Future Directions on Nanoparticles for Tumor Molecular Imaging, Int J Nanomedicine, 2024.

2. Hodo Y et al., Imaging the uptake and metabolism of glutamine in prostate tumor models using CEST MRI, Npj Imaging, 2025.

3. Hu FX et al., Preparation of Fe-Mn codoped 2D MXene nanoprobes and feasibility study of combining with CEST for multimodal imaging, NMR Biomed, 2025.

4. Yue H et al., Core-shell Fe3O4@C nanoparticles as highly effective T2 magnetic resonance imaging contrast agents: in vitro and in vivo studies, Nanomaterials, 2024.

5. Alemi PS et al., Carboxymethyl chitosan and chitosan as a bioactive delivery system: a review, Biotechnol Appl Biochem, 2025.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/660-03-008