Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
331-03-007 / 331-03-007 ISMRM Abstract

Iron-Related FC and cognitive impairment in NMOSD: Neurotransmitter, Cellular and Metabolic Correlates

Primary: Neuro
Secondary: Brain Function and fMRI - Functional Connectivity
331-03-007 · Clinical Applications in Psychiatry and Neurology · Monday, 11 May, 4:10 PM–5:36 PM · Roof Terrace
331-03-007 · Clinical Applications in Psychiatry and Neurology · Monday, 11 May, 4:10 PM–5:36 PM · Roof Terrace
Keywords: Functional Connectivity Cognitive impairment Quantitative Susceptibility Mapping (QSM) Neuromyelitis optica spectrum disorder JuSpace
Accepted
Xi Li 1, Bing Liu1, Fuyan Li1, Longji Xu1, Xiaoxia Lin2,3, Jing Wang1, Yuxi Liu1, Wenjing zhang1, Xiuzheng Yue4, Xinwu Ma1, Fuxin Ren1, Fei Gao1
1Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
2Department of Radiology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
3Department of Ultrasound, Jinan Municipal Hospital of Traditional Chinese Medicine, Jinan, China
4Clinical and Technical Support, Philips Healthcare (Beijing), Beijing, China
Presenting Author: Xi Li

Synopsis

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References

1. 1. Carnero Contentti E and Correale J. Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies. Journal of Neuroinflammation. 2021; 18: 208.
2. 2. Jarius S and Wildemann B. Aquaporin‐4 antibodies (NMO‐IgG) as a serological marker of neuromyelitis optica: a critical review of the literature. Brain pathology. 2013; 23: 661-83.
3. 3. Costello F. Neuromyelitis optica spectrum disorders. CONTINUUM: Lifelong Learning in Neurology. 2022; 28: 1131-70.
4. 4. Tham M, Frischer JM, Weigand SD, et al. Iron heterogeneity in early active multiple sclerosis lesions. Annals of neurology. 2021; 89: 498-510.
5. 5. Huang C, Li Y, Chen Y, et al. Correlation between cerebral cortex changes and clinical features in patients with neuromyelitis optica spectrum disorder with normal-appearing brain tissue: a case-control study. Neural Regeneration Research. 2023; 18: 2520-5.
6. 6. Fujiwara E, Kmech J, Cobzas D, et al. Cognitive implications of deep gray matter iron in multiple sclerosis. American Journal of Neuroradiology. 2017; 38: 942-8.
7. 7. Yongliang H, Liu Y, Chun Z, et al. Functional Connectivity Alterations in Neuromyelitis Optica Spectrum Disorder. Clinical Neuroradiology. 2020; 30: 559-68.
8. 8. Yang Y, Rui Q, Wu X, et al. Altered functional connectivity associated with cognitive impairment in neuromyelitis optica spectrum disorder. Multiple Sclerosis and Related Disorders. 2022; 68: 104113.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/331-03-007