366-04-015 ISMRM Abstract

Acute MEMRI Associates With Chronic Scar Burden and Left Ventricular Remodeling After Myocardial Ischemia-Reperfusion

Primary: Preclinical Animal & in vitro MR - Biomarkers

Secondary: Cardiovascular - Myocardium

366-04-015 · Probes and Targets · Monday, 11 May, 2:45 PM–3:40 PM · Digital Posters Row G

Keywords: Molecular Imaging Myocardial remodeling Myocardial ischemia Animal mouse model MEMRI

Accepted

Matic Pusovnik ¹, Ellen Calluwe², Swannie Pedron³, Thomas Bonnard³, Willy GSELL⁴, Stefan Janssens², Uwe Himmelreich¹

¹Biomedical MRI, KU Leuven, Leuven, Belgium

²Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

³INSERM U1237 Phind, tPA and Neurovascular Disorders, France

⁴Bruker BioSpin, Ettlingen, Germany

Presenting Author: Matic Pusovnik

Synopsis

Motivation:

Goals:

Approach:

Results:

Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

References

1. Jefferson A, Ruparelia N, Choudhury RP. Exogenous Microparticles of Iron Oxide Bind to Activated Endothelial Cells but, Unlike Monocytes, Do Not Trigger an Endothelial Response. Theranostics 3: 428–436, 2013. doi: 10.7150/thno.5895 [doi]

2. Heidt T, Reiss S, Thielmann J, Weber C, Maier A, Lottner T, Cristina-Schmitz HR, Bühler T, Chiang D, Jülicher C, Wadle C, Hilgendorf I, Wolf D, Tumlinson G, Hortells L, Westermann D, Bock M, von zur Mühlen C. Interventional real-time molecular MRI for targeting early myocardial injury in a pig model. npj Imaging 3: 7, 2025. doi: 10.1038/s44303-025-00069-z [doi]

3. Belliere J, Martinez de Lizarrondo S, Choudhury RP, Quenault A, Le Béhot A, Delage C, Chauveau D, Schanstra JP, Bascands J-L, Vivien D, Gauberti M. Unmasking Silent Endothelial Activation in the Cardiovascular System Using Molecular Magnetic Resonance Imaging. Theranostics 5: 1187–1202, 2015. doi: 10.7150/thno.11835. [doi]

4. Medzikovic L, Azem T, Sun W, Rejali P, Esdin L, Rahman S, Dehghanitafti A, Aryan L, Eghbali M. Sex Differences in Therapies against Myocardial Ischemia-Reperfusion Injury: From Basic Science to Clinical Perspectives. Cells 12: 2077, 2023. doi: 10.3390/cells12162077. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/366-04-015