Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
364-05-005 ISMRM Abstract

Time-Dependent Diffusion MRI Reveals Microstructural Predictors of Lymph Node Metastasis in Papillary Thyroid Carcinoma

Accepted
Shuai Wang1,2, jiayue Dai1,3, Wenlei Guo4, Zhen Jia1,2, SHAOXIN xiang5,6, Tianjiao Chen1, Miaomiao Wang4, Yan Zhang1, Xianjun Li4, Ting Liang 1, jian Yang1
1The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
2School of Future Technology, Xi'an Jiaotong University, Xi'an, China
3School of Mechanical Engineering, Xi’an Jiaotong University, Xi'an City, Shaanxi, China
4Department of Radiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
5MR Scientific Collaboration, United Imaging Healthcare, Shanghai, China
6Shanghai United Imaging Healthcare Co., Ltd, Shanghai, China
Presenting Author: Ting Liang

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Boucai, L.; Zafereo, M.; Cabanillas, M. E. Thyroid Cancer: A Review. Jama 2024, 331 (5), 425-435. DOI: 10.1001/jama.2023.26348 [doi]
2. Forma, A.; Kłodnicka, K.; Pająk, W.; Flieger, J.; Teresińska, B.; Januszewski, J.; Baj, J. Thyroid Cancer: Epidemiology, Classification, Risk Factors, Diagnostic and Prognostic Markers, and Current Treatment Strategies. Int J Mol Sci 2025, 26 (11). DOI: 10.3390/ijms26115173 [doi]
3. Zhao, Z. L.; Wang, S. R.; Dong, G.; Liu, Y.; He, J. F.; Shi, L. L.; Guo, J. Q.; Wang, Z. H.; Cong, Z. B.; Liu, L. H.; et al. Microwave Ablation versus Surgical Resection for US-detected Multifocal T1N0M0 Papillary Thyroid Carcinoma: A 10-Center Study. Radiology 2024, 311 (1), e230459. DOI: 10.1148/radiol.230459 [doi]
4. Liu, F.; Wu, L.; Luo, X.; Li, S.; Wang, Y.; Zhong, W.; Feiweier, T.; Xu, J.; Shi, D.; Bao, H.; et al. Evaluating the Diagnostic Performance of MR Cytometry Imaging in Differentiating Benign and Malignant Breast Tumors. J Magn Reson Imaging 2025, 62 (2), 521-533. DOI: 10.1002/jmri.29757 [doi]
5. Zhang, L.; Long, X.; Chen, L.; Han, X.; Zhang, X.; Sun, P.; Yang, Y.; Fan, J.; Wang, J.; Lei, Z.; et al. Detecting Cellular Microstructural Changes of Liver Fibrosis with Time-Dependent Diffusion MRI. Radiology 2024, 313 (1), e240343. DOI: 10.1148/radiol.240343 [doi]
6. Wu, D.; Jiang, K.; Li, H.; Zhang, Z.; Ba, R.; Zhang, Y.; Hsu, Y. C.; Sun, Y.; Zhang, Y. D. Time-Dependent Diffusion MRI for Quantitative Microstructural Mapping of Prostate Cancer. Radiology 2022, 303 (3), 578-587. DOI: 10.1148/radiol.211180 [doi]
7. Jiang, X.; Li, H.; Xie, J.; Zhao, P.; Gore, J. C.; Xu, J. Quantification of cell size using temporal diffusion spectroscopy. Magn Reson Med 2016, 75 (3), 1076-1085. DOI: 10.1002/mrm.25684 [doi]
8. Jolly, L. A.; Novitskiy, S.; Owens, P.; Massoll, N.; Cheng, N.; Fang, W.; Moses, H. L.; Franco, A. T. Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss. Cancer Res 2016, 76 (7), 1804-1813. DOI: 10.1158/0008-5472.Can-15-2351 [doi]
9. Li, R.; Zhao, M.; Sun, M.; Wu, Y.; Miao, C.; Fangyu, L.; Wu, M.; Shi, X.; Lu, J.; Yue, X. P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway. Cancer Cell Int 2025, 25 (1), 249. DOI: 10.1186/s12935-025-03871-2 [doi]
10. Winkler, J.; Abisoye-Ogunniyan, A.; Metcalf, K. J.; Werb, Z. Concepts of extracellular matrix remodelling in tumour progression and metastasis. Nat Commun 2020, 11 (1), 5120. DOI: 10.1038/s41467-020-18794-x [doi]
11. Liang, W.; Chen, J.; Li, H.; Zhang, P.; Guan, H.; Li, Y. High expression of COL8A1 predicts poor prognosis and promotes EMT in papillary thyroid cancer. Endocr Connect 2024, 13 (12). DOI: 10.1530/ec-24-0279 [doi]

Cite this abstract