462-01-006 ISMRM Abstract

A Multimodal MRI Study Reveals Thalamic Neurovascular-Neurochemical Decoupling in Classical Trigeminal Neuralgia

Primary: Contrast Mechanisms - Arterial Spin Labelling

Secondary: Neuro - Peripheral Nerves

462-01-006 · Contrast Mechanisms Potpourri Including Registered/Clinical Abstracts · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row C

Keywords: Cerebral blood flow Gamma-aminobutyric acid Thalamus Classical Trigeminal Neuralgia Magnetic Resonance Spectroscopy

Accepted

jingqi Jiang¹, Danyang Wang¹, Pengfei Zhang², Kai AI³, Jing Zhang ⁴

¹Department of Magnetic Resonance, Lanzhou, China

²West China Hospital of Sichuan University, Chendu, China

³Department of Clinical and Technical Support, Philips Healthcare (Xi'an), Xi'an, China

⁴The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China

Presenting Author: Jing Zhang

Synopsis

Motivation:

Goals:

Approach:

Results:

Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

References

1. Watanabe M, Shrivastava RK, Balchandani P. Advanced neuroimaging of the trigeminal nerve and the whole brain in trigeminal neuralgia: a systematic review. Pain. 2025;166(2):282-310.

2. Chen Z, Liu Y, Lin C, et al. Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study. J Headache Pain. 2024;25(1):84.

3. Liu CH, Feng HJ, Peng F, et al. Involvement of mediodorsal thalamus and its related neural circuit in pain regulation in mice. Neurobiol Dis. 2025;215:107056.

4. Xiong J, Liu M, Li X,. Altered perfusion in the locus coeruleus of patients with chronic migraine: a pilot 3D-PCASL study. et al Brain Imaging Behav. 2025;19(4):930-937.

5. Treacy C, Andrews SC, Levenstein JM. Relationships between GABA + and Glx concentrations with age and inhibition in healthy older adults. Brain Struct Funct. 2025;230(8):149.

6. Yoon S, Won W, Lee S, et al. Astrocytic gamma-aminobutyric acid dysregulation as a therapeutic target for posttraumatic stress disorder. Signal Transduct Target Ther. 2025;10(1):240.

7. Krishnamurthy V, Krishnamurthy LC. CBF gradient and excitatory-inhibitory balance measured from pre-SMA - importance in aging and semantic fluency task difficulties. Neuroimage. 2025;320:121451.

8. Cai SQ, Tian Y, Zhang ZX, et al. Contribution of thalamo-cortico-limbic circuits to remifentanil-induced hyperalgesia (RIH) and the analgesic effects of electroacupuncture on RIH. Brain Res Bull. 2025;232:111582.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/462-01-006