Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
366-04-014 ISMRM Abstract

MRI-Visible Biomimetic Macrophage Membrane Nanoplatform for Theranostic Modulation of Doxorubicin-Induced Myocardial Injury

Accepted
ZhiNan Wang 1, Xi Liu1, Yingshi Sun1
1Peking University Cancer Hospital & Institute, Beijing, China
Presenting Author: ZhiNan Wang

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. DeSantis CE, Siegel RL, Sauer AG, et al. Cancer statistics for African Americans, 2016: Progress and opportunities in reducing racial disparities. CA Cancer J Clin. 2016;66(4):290-308. doi:10.3322/caac.21340 [doi]
2. Paskeh MDA, Saebfar H, Mahabady MK, et al. Overcoming doxorubicin resistance in cancer: siRNA-loaded nanoarchitectures for cancer gene therapy. Life Sci. 2022;298:120463. doi:10.1016/j.lfs.2022.120463 [doi]
3. Shi S, Chen Y, Luo Z, Nie G, Dai Y. Role of oxidative stress and inflammation-related signaling pathways in doxorubicin-induced cardiomyopathy. Cell Commun Signal. 2023;21(1):61. Published 2023 Mar 14. doi:10.1186/s12964-023-01077-5 [doi]
4. Liang X, Wang S, Wang L, Ceylan AF, Ren J, Zhang Y. Mitophagy inhibitor liensinine suppresses doxorubicin-induced cardiotoxicity through inhibition of Drp1-mediated maladaptive mitochondrial fission. Pharmacol Res. 2020;157:104846. doi:10.1016/j.phrs.2020.104846 [doi]
5. Kim M, Xin R, Earnshaw J, et al. MOF-derived nanoporous carbons with diverse tunable nanoarchitectures. Nat Protoc. 2022;17(12):2990-3027. doi:10.1038/s41596-022-00718-2 [doi]
6. Sahu A, Jeon J, Lee MS, Yang HS, Tae G. Antioxidant and anti-inflammatory activities of Prussian blue nanozyme promotes full-thickness skin wound healing. Mater Sci Eng C Mater Biol Appl. 2021;119:111596. doi:10.1016/j.msec.2020.111596 [doi]
7. Forouzanfar F, Pourbagher-Shahri AM, Darroudi M, et al. Cerium Oxide Nanoparticles Ameliorate Oxidative Stress, Inflammation, and Pain Behavior in Neuropathic Rats. Curr Neurovasc Res. 2023;20(1):54-61. doi:10.2174/1567202620666230125104604 [doi]
8. Wang J, Wang Y, Xiaohalati X, et al. A Bioinspired Manganese-Organic Framework Ameliorates Ischemic Stroke through its Intrinsic Nanozyme Activity and Upregulating Endogenous Antioxidant Enzymes. Adv Sci (Weinh). 2023;10(20):e2206854. doi:10.1002/advs.202206854 [doi]
9. Somebang K, Rudolph J, Imhof I, et al. CCR2 deficiency alters activation of microglia subsets in traumatic brain injury. Cell Rep. 2021;36(12):109727. doi:10.1016/j.celrep.2021.109727 [doi]
10. Rong Y, Ji C, Wang Z, et al. Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury. J Neuroinflammation. 2021;18(1):196. Published 2021 Sep 12. doi:10.1186/s12974-021-02268-y [doi]

Cite this abstract