Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
462-01-008 Registered Abstract

Multi-site, Multi-Vendor Quality Assurance Phantom Validation for 129Xe MRI Clinical Trials Consortium Protocols

Primary: Contrast Mechanisms - Hyperpolarized MR (Gas)
Secondary: Physics & Engineering - Phantoms
462-01-008 · Contrast Mechanisms Potpourri Including Registered/Clinical Abstracts · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row C
Keywords: Hyperpolarized Xenon-129 MRI Quality Assurance Phantom study Repeatability and reproducibility Multi-vendor
Accepted
Mariah L Costa1, Conner J Wharff1,2, Riley B Meyer3,4, Saman Khodaei4, Andrew D Hahn1,5,6, Abhilash Kizhakke Puliyakote1, Sean Fain 1,3,4
1Department of Radiology, University of Iowa, Iowa City, United States of America
2University of Iowa; Department of Radiology, University of Iowa, Iowa City, United States of America
3University of Iowa, Iowa City, United States of America
4Roy J. Carver Department of Biomedical Engineering, University of Iowa, Iowa City, United States of America
5University of Iowa; Department of Radiology, University of Iowa, Iowa City, United States of America
6University of Iowa; University of Iowa — Department of Radiology, University of Iowa, Iowa City, United States of America
Presenting Author: Sean Fain

Synopsis

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References

1. Polarean, FDA expands Xenoview® indication to include children from six years of age. News release.
2. Polarean, Xenoview. Package insert. 2025.
3. Niedbalski, P.J., et al., Protocols for multi-site trials using hyperpolarized (129) Xe MRI for imaging of ventilation, alveolar-airspace size, and gas exchange: A position paper from the (129) Xe MRI clinical trials consortium. Magn Reson Med, 2021. 86(6): p. 2966-2986. doi:10.1002/mrm.28985. [doi]
4. Bier, E.A., et al., A thermally polarized (129) Xe phantom for quality assurance in multi-center hyperpolarized gas MRI studies. Magn Reson Med, 2019. 82(5): p. 1961-1968. doi:10.1002/mrm.27836. [doi]
5. Lashansky, S., et al., Edge response revisited. SPIE Defense and Security Symposium. Vol. 6941. 2008: SPIE. doi:10.1117/12.777957. [doi]
6. National Electrical Manufacturers Association, Determination of Slice Thickness in Diagnostic Magnetic Resonance Imaging. 2018, NEMA.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/462-01-008